Tag Heptane

nQuality Industrial Solvent from Junyuan Petroleum Group

n-Heptane, 99%: A High-Quality Industrial Solvent from Junyuan Petroleum Group

Simple Keywords: n-Heptane, Very Pure, Industrial Use, Junyuan Petroleum Group, Largest Producer, Drums, Shipping Containers, ISO Tanks

Short Summary:

n-Heptane, 99% is a high-quality industrial solvent produced by Junyuan Petroleum Group, China’s largest producer of this product. We offer it in various packaging sizes, from drums to large shipping containers and ISO tanks, to suit your needs. This article provides more information about n-Heptane, 99%, Junyuan Petroleum Group’s background, and how we can send the product to you.


n-Heptane, 99%: A High-Quality Industrial Solvent from Junyuan Petroleum Group

n-Heptane is a clear liquid with a chemical formula of C7H16, widely used in industry due to its purity and dissolving capabilities. Junyuan Petroleum Group, as China’s largest producer of n-Heptane, 99%, offers this product with exceptional quality and reliability.

Junyuan Petroleum Group: A Brief Background

Junyuan Petroleum Group was established in 2009 and is based in Dongying, in China’s beautiful Yellow River Delta. The group has grown into a comprehensive enterprise with multiple subsidiaries, focusing on the comprehensive development and utilization of oil and gas resources. With a strong commitment to innovation and technology, Junyuan has become a leading producer of high-quality petrochemical products, including n-Heptane, 99%.

What Makes Our n-Heptane, 99% Special?

  • Very Pure: Our n-Heptane is 99% pure, ensuring accurate and reliable results in various industrial applications.
  • Dissolves Well: Its excellent dissolving capabilities make it suitable for a wide range of industrial solvents.
  • Stable: With low volatility, it reduces evaporation losses during storage and use.
  • Safe and Eco-Friendly: Meeting environmental standards, our n-Heptane is safer for both people and the environment.

How We Package It

To suit your diverse needs, we offer n-Heptane, 99% in various packaging sizes:

  • Drums: Each drum contains 137 kilograms (kg). In a 20-foot shipping container, you can fit 80 drums, totaling 10.96 metric tons (MT). A 40-foot high-cube container can hold 160 drums, totaling 21.92 MT.
  • ISO Tanks: For larger quantities, we provide ISO tanks capable of holding up to 16.8 MT (about 26 cubic meters) of n-Heptane.

How We Ship It

We offer flexible shipping options to ensure safe and efficient delivery of n-Heptane, 99%:

  • By Sea: Utilizing 20-foot or 40-foot shipping containers for international shipping.
  • By Land: ISO tanks are ideal for long-distance land travel within China, minimizing losses and risks.
  • Delivery Services: Comprehensive delivery services ensure a seamless journey from our factory to your location.

Where It’s Used

Our n-Heptane, 99% finds applications in numerous industries, including:

  • Chemical Manufacturing: As a raw material for paints, coatings, and adhesives.
  • Natural Product Extraction: Facilitating the extraction of essential oils and pharmaceutical ingredients.
  • Cleaning and Degreasing: Effective for cleaning metal surfaces and removing grease.
  • Fuel Additives: Enhancing fuel efficiency and stability.

As China’s largest producer of n-Heptane, 99%, Junyuan Petroleum Group is committed to providing high-quality products and services. With various packaging and shipping options, we can meet your needs for this versatile industrial solvent. For more information, feel free to contact us.

Pentane, Hexane and Heptane Prices, Upstream, Downstream, Analytics & Forecasts
Junyuan Petroleum Group – Dongying Liangxin Petrochemical Technology Development Limited Company | Address: No. 117, Guangqing Rd., Guangrao County, Dongying 257345 China.
Junyuan Petroleum Group is China’s largest manufacturer of blowing agents to the foam insulation markets. We have continued to grow with the development of next generation blowing agents, offering a variety of hydrocarbon products for the PIR, PUR and EPS markets, available in ISO tanks and drums. For more information, or for pricing please contact us: +86 178 1030 0898 Email: info@junyuanpetroleumgroup.com Web: www.junyuanpetroleumgroup.com.
China is the world’s largest buyer and drives prices in Asia and the global solvent trade. Our comprehensive news and pricing coverage of China and global solvent market is constantly updated by our raw material purchase, production and sales team of experts. Solvent markets can react to change quickly. It’s crucial for buyers, sellers and producers to stay alert and aware of what’s happening, both in their region and internationally. We help you stay abreast of change as it’s happening. We keep you informed of the current price and market position, so you can make the most of opportunities to trade or secure a deal.

The Truth Behind the Recent Surge in n-Heptane Prices

The Truth Behind the Recent Surge in n-Heptane Prices

I. Introduction

Recently, the price of n-Heptane has experienced a sharp increase, attracting widespread attention from various industries. Whether it’s chemical enterprises, related manufacturing sectors, or investors, there is an urgent need to understand the underlying causes. As an important chemical raw material, n-Heptane has a wide range of applications in numerous fields. Its price fluctuations will inevitably have a profound impact on the entire industrial chain.

II. Transmission of Crude Oil Price Fluctuations

n-Heptane, as a petrochemical derivative, is closely related to crude oil prices. The international crude oil market is like a huge “butterfly effect” hub, where any minor disturbance can affect the price of n-Heptane.

(A) Geopolitical Factors
Geopolitical conflicts have always been a crucial factor influencing crude oil prices. For example, the unstable situation in the Middle East region poses a threat to oil supply. During the Iraq War, international oil prices soared significantly. When the supply of crude oil is at risk of decreasing, the production costs of petrochemical products, including n-Heptane, will inevitably rise.

(B) Production Regulation by OPEC+
OPEC+ (Organization of the Petroleum Exporting Countries and its allies) plays a vital role in the global oil market. When they decide to cut production to stabilize oil prices or raise them, the entire petrochemical industry chain is affected. For instance, when OPEC+ decided to cut production to address the issue of high global oil inventories, the supply of crude oil decreased, leading to an increase in the prices of petrochemical raw materials and, consequently, n-Heptane.

III. Structural Imbalance between Supply and Demand

(A) Changes in Demand
1. Growth in Demand in the Chemical Field
In the chemical industry, n-Heptane is a high-quality solvent. With the continuous development of industries such as coatings and adhesives, the demand for n-Heptane has been increasing. For example, the significant growth in demand for building materials has led to an increased use of coatings, which in turn has boosted the demand for n-Heptane as a solvent.
2. Expansion in Emerging Application Fields
n-Heptane also has important applications in pharmaceutical intermediates and nylon 66 monomer raw materials. In recent years, with the innovation and development of the pharmaceutical industry and the research and development needs of high-performance materials, the demand for n-Heptane in these emerging fields has been growing.

(B) Constraints on Supply
1. Capacity Maintenance and Accidents
If major production enterprises conduct equipment maintenance or experience accidents, the production of n-Heptane will decrease. For example, during the annual equipment maintenance period of a large petrochemical enterprise, the supply of n-Heptane will significantly decline.
2. Environmental Protection Production Limitations
To achieve carbon peak and carbon neutrality goals, many regions have introduced environmental protection production limitation policies. Some traditional petrochemical enterprises that fail to meet environmental protection standards are forced to reduce or suspend production, resulting in a decrease in the supply of n-Heptane.

IV. Policy and Environmental Driving Forces

(A) Substitution Effect
EU’s “Green Deal” and other environmental protection policies have promoted the substitution process of chemical raw materials. As a relatively low-toxicity solvent, n-Heptane can replace traditional toxic solvents such as benzene-based solvents in many fields. With the strengthening of environmental protection policies, the market demand for n-Heptane has further expanded.

(B) Carbon Emission Costs
The expansion of the carbon trading market has increased the production costs of petrochemical enterprises. To meet carbon emission requirements, enterprises need to invest more funds in energy conservation, emission reduction, or purchasing carbon emission quotas. These costs will ultimately be passed on to product prices, leading to an increase in the price of n-Heptane.

V. Transportation and Logistics Bottlenecks

(A) Impact of Energy Crisis
The global energy crisis has led to a significant increase in transportation costs. For example, the conflict between Russia and Ukraine has caused energy supply tensions in Europe, with shipping freight rates soaring. As the transportation of n-Heptane mainly relies on sea transport, the increase in transportation costs will inevitably push up its price.

(B) Regional Transportation Restrictions
Logistics control measures in certain regions can also affect the supply of n-Heptane. For instance, labor disputes at some ports in the United States have led to strikes, causing goods transportation to be disrupted and affecting the supply of n-Heptane.

VI. Speculation and Market Expectations

(A) Hoarding Behavior
In the market, some traders expect a future shortage of n-Heptane or a surge in demand and, therefore, hoard large amounts of n-Heptane in advance. This hoarding behavior reduces the market supply in the short term, thereby pushing up prices.

(B) Linkage with the Futures Market
Fluctuations in crude oil futures prices are transmitted to the spot market of n-Heptane through financial derivatives. If crude oil futures prices rise, investors will expect the price of n-Heptane to increase as well and engage in speculation in the spot market, further driving up prices.

VII. Seasonal Factors

(A) Production Off-Season
In some regions, n-Heptane production facilities enter the maintenance period during specific seasons, resulting in a decrease in production. For example, in cold winters, some enterprises choose to suspend production for maintenance to ensure the safe operation of equipment.

(B) Consumption Peak Season
Some industries have consumption peak seasons, during which the demand for n-Heptane increases significantly. For example, the construction coating industry experiences a peak demand for n-Heptane during the summer construction season.

VIII. Recommendations

(A) Diversification of the Supply Chain
Enterprises should reduce their reliance on a single supplier or import source and seek multiple supply channels to reduce supply risks.

(B) Technological Upgrading
Increase investment in research and development to develop efficient production processes or find alternative raw materials, such as biomass-based n-Heptane, to reduce costs.

(C) Policy Monitoring
Closely monitor changes in environmental protection regulations and trade policies of various countries and adjust production and business strategies in a timely manner.

(D) Long-Term Contract Locking
Sign long-term price agreements with suppliers to hedge against price fluctuations to a certain extent.

IX. Conclusion

The recent surge in n-Heptane prices is the result of the combined effect of multiple factors. From the fluctuation of crude oil prices to the imbalance of supply and demand, from the impact of policies and environmental protection to transportation and logistics bottlenecks, and then to speculative expectations and seasonal factors, each link is interrelated. Related enterprises and investors need to have a comprehensive and in-depth understanding of these factors to make correct decisions in market changes.

Pentane, Hexane and Heptane Prices, Upstream, Downstream, Analytics & Forecasts
Junyuan Petroleum Group – Dongying Liangxin Petrochemical Technology Development Limited Company | Address: No. 117, Guangqing Rd., Guangrao County, Dongying 257345 China.
Junyuan Petroleum Group is China’s largest manufacturer of blowing agents to the foam insulation markets. We have continued to grow with the development of next generation blowing agents, offering a variety of hydrocarbon products for the PIR, PUR and EPS markets, available in ISO tanks and drums. For more information, or for pricing please contact us: +86 178 1030 0898 Email: info@junyuanpetroleumgroup.com Web: www.junyuanpetroleumgroup.com.
China is the world’s largest buyer and drives prices in Asia and the global solvent trade. Our comprehensive news and pricing coverage of China and global solvent market is constantly updated by our raw material purchase, production and sales team of experts. Solvent markets can react to change quickly. It’s crucial for buyers, sellers and producers to stay alert and aware of what’s happening, both in their region and internationally. We help you stay abreast of change as it’s happening. We keep you informed of the current price and market position, so you can make the most of opportunities to trade or secure a deal.

Chemical Product Price Analysis Report (USD Pricing, February 4, 2025, Based on Real-Time Exchange Rate of 7.2497)

I. Isopentane

Today, the price of isopentane with 95% purity is approximatelyUSD 1,106.14 per ton(not in drums, price to be negotiated); the price of isopentane with 99% purity is approximatelyUSD 1,231.51 per ton(not in drums, price to be negotiated).

II. Pentane Mixture

Today, the price of the pentane mixture (assuming a composition similar to that of isopentane for pricing purposes) is approximatelyUSD 1,113.37 per ton.

III. Food-Grade n-Hexane

Today, the price of food-grade n-hexane with 60% and 80% purity is approximatelyUSD 1,113.37 per ton; the price of 99% purity is approximatelyUSD 1,375.68 per ton. If customers have strict requirements for aromatic hydrocarbon content (less than 10ppm), an additional fee will be charged.

IV. n-Heptane

Today, the price of n-heptane is approximatelyUSD 2,346.23 per ton. If drums are selected, an additional drumming fee will be charged (specific amount to be negotiated). If customers have strict requirements for aromatic hydrocarbon content (less than 10ppm), the price will also increase.

V. High-Purity Isobutane

Today, the price of high-purity isobutane is approximatelyUSD 1,005.97 per ton(price to be negotiated).

VI. Industrial Hexane and Cyclopentane

Today, the ex-factory price of industrial hexane is approximatelyUSD 1,744.41 per ton(drumming fee and drum cost extra); the price of cyclopentane is approximatelyUSD 1,976.12 per ton.

Exchange Rate Note: The above prices have been converted based on the real-time exchange rate of 7.2497 Chinese yuan to US dollars on February 4, 2025. Customers are advised to confirm the prices with the supplier before making any transactions, as market conditions and exchange rate fluctuations may affect the final prices.

Chemical Product Price Analysis Report (USD Pricing, February 4, 2025, Based on Real-Time Exchange Rate of 7.2497)

I. Isopentane

Today, the price of isopentane with 95% purity is approximatelyUSD 1,106.14 per ton(not in drums, price to be negotiated); the price of isopentane with 99% purity is approximatelyUSD 1,231.51 per ton(not in drums, price to be negotiated).

II. Pentane Mixture

Today, the price of the pentane mixture (assuming a composition similar to that of isopentane for pricing purposes) is approximatelyUSD 1,113.37 per ton.

III. Food-Grade n-Hexane

Today, the price of food-grade n-hexane with 60% and 80% purity is approximatelyUSD 1,113.37 per ton; the price of 99% purity is approximatelyUSD 1,375.68 per ton. If customers have strict requirements for aromatic hydrocarbon content (less than 10ppm), an additional fee will be charged.

IV. n-Heptane

Today, the price of n-heptane is approximatelyUSD 2,346.23 per ton. If drums are selected, an additional drumming fee will be charged (specific amount to be negotiated). If customers have strict requirements for aromatic hydrocarbon content (less than 10ppm), the price will also increase.

V. High-Purity Isobutane

Today, the price of high-purity isobutane is approximatelyUSD 1,005.97 per ton(price to be negotiated).

VI. Industrial Hexane and Cyclopentane

Today, the ex-factory price of industrial hexane is approximatelyUSD 1,744.41 per ton(drumming fee and drum cost extra); the price of cyclopentane is approximatelyUSD 1,976.12 per ton.

Exchange Rate Note: The above prices have been converted based on the real-time exchange rate of 7.2497 Chinese yuan to US dollars on February 4, 2025. Customers are advised to confirm the prices with the supplier before making any transactions, as market conditions and exchange rate fluctuations may affect the final prices.

Connecting Central Asia and Russia

Did you know that n-Hexane, n-Pentane, Cyclopentane, n-Heptane, and Isohexane can be transported by road to various countries in Central Asia and Russia? These hydrocarbons play a crucial role in energy production and industrial processes. 🚚🌏 #Hexane #Heptane #Pentane #Cyclopentane #Isohexane #ChemicalTransport #EnergyIndustry

Feel free to share this information with your network! 😊👍

The application of n-Heptane in the rubber industry


The application of n-Heptane in the rubber industry is indeed extensive. Here are some specific cases:

1. Rubber processing: n-Heptane is used as a solvent in the rubber processing process. It helps in the mixing, plasticization and molding of rubber.

2. Rubber product manufacturing: n-Heptane is used to manufacture various rubber products, such as tires, seals, rubber tubes, rubber pads, etc. It can improve the fluidity and processing properties of rubber.

3. Rubber adhesives: n-Heptane is also used as one of the ingredients of rubber adhesives. It helps to bond different parts together.

In short, n-Heptane plays an important role in the rubber industry and supports the manufacturing and performance of rubber products. If you need more detailed information or other help, please feel free to let us know!


Dimethyl Disulfide (DMDS): Catalyst Sulfiding and Advantages

Dimethyl Disulfide (DMDS): Catalyst Sulfiding and Advantages

What is n-Heptane and why is it important for chemistry?

n-Heptane is a pure form of heptane, a common solvent and fuel component. It has a special role in measuring the octane rating of gasoline and in separating chiral compounds.

Heptane is a simple organic compound with the chemical formula C$_7$H$_{16}$. It is a colorless liquid that smells like gasoline and is highly flammable. Heptane is widely used as a solvent in laboratories and industries, as it can dissolve many non-polar substances. It is also a component of gasoline, as it can be easily refined from crude oil.

However, not all heptane molecules are the same. There are different ways to arrange the seven carbon atoms and the 16 hydrogen atoms in a heptane molecule, resulting in different shapes and properties. These different forms of heptane are called isomers, and there are nine of them in total.

One of the isomers of heptane is n-heptane, which stands for normal heptane. This is the simplest and most symmetrical form of heptane, where the seven carbon atoms are arranged in a straight chain. n-Heptane has some unique characteristics that make it important for chemistry.

First, n-heptane is the standard for measuring the octane rating of gasoline. The octane rating is a measure of how well a fuel can resist knocking, which is a phenomenon where the fuel ignites too early in the engine, causing damage and reducing efficiency. n-Heptane is very prone to knocking, as it burns very quickly and explosively. Therefore, it is assigned a octane rating of zero, meaning the worst possible fuel for an engine. On the other hand, iso-octane, another isomer of octane (C$_8$H$_{18}$), is very resistant to knocking, as it burns more slowly and smoothly. Therefore, it is assigned a octane rating of 100, meaning the best possible fuel for an engine. Other fuels are compared to these two extremes, and their octane rating is calculated as the percentage of iso-octane in a mixture with n-heptane that has the same knocking behavior. For example, a gasoline with an octane rating of 87 means that it behaves like a mixture of 87% iso-octane and 13% n-heptane.

Second, n-heptane is useful for separating chiral compounds. Chiral compounds are molecules that have two forms that are mirror images of each other, like your left and right hands. These forms are called enantiomers, and they can have different effects on living organisms. For example, one enantiomer of a drug may be beneficial, while the other may be harmful. Therefore, it is important to be able to separate and identify the enantiomers of a chiral compound. One way to do this is by using a chiral column, which is a tube filled with a material that can distinguish between the enantiomers. The chiral compound is dissolved in a solvent, such as n-heptane, and passed through the column. The enantiomers will interact differently with the material, and will come out of the column at different times. This is called chromatography, and it is a widely used technique for separating and analyzing mixtures.

n-Heptane is a good solvent for chiral chromatography, as it is non-polar and does not interfere with the interactions between the enantiomers and the material. However, n-heptane alone is not enough to separate the enantiomers, as it may not have enough eluting power, which is the ability to push the compounds through the column. Therefore, n-heptane is often mixed with other solvents, such as ethanol or isopropanol, which have more eluting power and can affect the selectivity and resolution of the separation. The choice of the solvent mixture is a key step in chiral analysis, and it depends on the properties of the chiral compound and the column material.

In summary, n-heptane is a pure form of heptane, a common solvent and fuel component. It has a special role in measuring the octane rating of gasoline and in separating chiral compounds. n-Heptane is an example of how a simple molecule can have important applications in chemistry and beyond.

How Much Hydrocarbon Can You Fit in a 200-Liter Steel Drum?

Abstract: Hydrocarbons are organic compounds that are widely used as fuels, solvents, and raw materials. In this article, we will explain how to calculate how much hydrocarbon you can fit in a 200-liter steel drum, using four examples: n-pentane, n-heptane, cyclopentane, and isohexane. We will use their densities and a safety filling factor of 95% to account for possible expansion or contraction due to temperature or pressure changes.

Keywords: hydrocarbons, density, net weight, safety filling factor, steel drum

Text:

Hydrocarbons are organic compounds that consist of only carbon and hydrogen atoms. They have different shapes and sizes, which affect their physical and chemical properties. Some hydrocarbons are straight chains, such as n-pentane and n-heptane. Some are rings, such as cyclopentane. Some have branches, such as isohexane. These hydrocarbons are widely used as fuels, solvents, and raw materials for various industries.

But how much hydrocarbon can you fit in a 200-liter steel drum? This is an important question for storing and transporting hydrocarbons safely and efficiently. To answer this question, we need to know two things: the density and the safety filling factor of the hydrocarbon.

The density of a substance is the mass per unit volume. It is usually expressed in grams per milliliter (g/mL) or kilograms per liter (kg/L). The density of a hydrocarbon depends on its molecular structure, temperature, and pressure. For this article, we will use the density values at 20°C and 1 atm, which are available from various sources¹²³⁴.

The safety filling factor is the percentage of the drum volume that can be safely filled with the hydrocarbon. We cannot fill the drum completely, because the hydrocarbon may expand or contract due to temperature or pressure changes. This could cause the drum to leak or burst, which could be dangerous and wasteful. Therefore, we need to leave some empty space in the drum to allow for possible expansion or contraction. For this article, we will use a safety filling factor of 95%, which means that we will fill the drum with 95% of its volume.

The net weight of a hydrocarbon in a drum is the mass of the hydrocarbon that fills the drum. To calculate the net weight, we need to multiply the volume of the drum by the density of the hydrocarbon and by the safety filling factor. The formula is:

$$W = V \times D \times F$$

where W is the net weight in kilograms (kg), V is the volume of the drum in liters (L), D is the density of the hydrocarbon in kilograms per liter (kg/L), and F is the safety filling factor as a decimal number (0.95).

The volume of a drum is the space that it occupies. It is usually expressed in liters (L) or cubic meters (m^3^). The volume of a drum depends on its shape and size. For this article, we will assume that the drum is cylindrical, with a height of 0.9 m and a diameter of 0.6 m. The volume of a cylindrical drum can be calculated by multiplying the area of the base by the height. The area of the base is the area of a circle, which can be calculated by multiplying pi (π) by the square of the radius. The radius is half of the diameter. Therefore, the volume of the drum is:

$$V = \pi r^2 h$$

$$V = \pi (0.3)^2 (0.9)$$

$$V = 0.254 m^3$$

$$V = 254 L$$

Now, we can calculate the net weight of each hydrocarbon in the drum, using the formula and the density values from the sources. The results are:

  • The net weight of n-pentane in the drum is:

$$W = 254 \times 0.626 \times 0.95$$

$$W = 150.7 kg$$

  • The net weight of n-heptane in the drum is:

$$W = 254 \times 0.679 \times 0.95$$

$$W = 164.1 kg$$

  • The net weight of cyclopentane in the drum is:

$$W = 254 \times 0.746 \times 0.95$$

$$W = 180.1 kg$$

  • The net weight of isohexane in the drum is:

$$W = 254 \times 0.659 \times 0.95$$

$$W = 159.1 kg$$

In conclusion, we have explained how to calculate how much hydrocarbon you can fit in a 200-liter steel drum, using four examples: n-pentane, n-heptane, cyclopentane, and isohexane. We have used their densities and a safety filling factor of 95% to account for possible expansion or contraction due to temperature or pressure changes. This article can help us understand how to store and transport hydrocarbons safely and efficiently.

Pharmaceutical-grade Heptane: Production Process and Applications

Abstract: Heptane is a hydrocarbon with the chemical formula C7H16. It is a colorless, volatile, and flammable liquid that is widely used as a solvent, fuel, and chemical intermediate. Pharmaceutical-grade heptane is a high-purity heptane that meets the standards of the United States Pharmacopeia (USP) and the European Pharmacopoeia (EP). It is mainly used as a solvent for the extraction, purification, and crystallization of active pharmaceutical ingredients (APIs). This article introduces the production process of pharmaceutical-grade heptane and its applications in the pharmaceutical industry.

Keywords: heptane, pharmaceutical-grade, solvent, extraction, purification, crystallization, API

Article:

Heptane is one of the simplest alkanes, a class of hydrocarbons that consist of only carbon and hydrogen atoms. It has seven carbon atoms and 16 hydrogen atoms, arranged in a straight chain or a branched structure. There are nine possible isomers of heptane, which differ in the way the carbon atoms are connected. The most common isomer is n-heptane, which has a straight-chain structure. Other isomers include isoheptane, methylhexane, dimethylpentane, and ethylpentane.

Heptane can be obtained from natural sources, such as crude oil and natural gas, or from synthetic sources, such as the catalytic cracking of petroleum or the Fischer-Tropsch process. Heptane is usually separated from other hydrocarbons by fractional distillation, a process that exploits the different boiling points of the components. Heptane has a boiling point of about 98°C, which is lower than that of octane (125°C) and higher than that of hexane (69°C).

Heptane has many industrial uses, such as a solvent, fuel, and chemical intermediate. As a solvent, heptane can dissolve or extract various organic compounds, such as fats, oils, waxes, resins, rubber, and plastics. As a fuel, heptane can be blended with other hydrocarbons to produce gasoline, jet fuel, and diesel. As a chemical intermediate, heptane can be used to synthesize other organic compounds, such as alcohols, ketones, aldehydes, and carboxylic acids.

Pharmaceutical-grade heptane is a special type of heptane that has a high purity and meets the specifications of the USP and the EP. These specifications include the limits of impurities, such as water, sulfur, aromatics, olefins, and other hydrocarbons. Pharmaceutical-grade heptane also has to pass certain tests, such as the assay, the density, the refractive index, the acidity, the peroxide value, and the residue on evaporation.

Pharmaceutical-grade heptane is mainly used as a solvent for the extraction, purification, and crystallization of APIs. APIs are the substances that are responsible for the therapeutic effects of drugs. They can be derived from natural sources, such as plants, animals, or microorganisms, or from synthetic sources, such as chemical synthesis or biotechnology. APIs have to be isolated and purified from the raw materials or the reaction mixtures, and then crystallized into solid forms that have the desired properties, such as purity, stability, solubility, bioavailability, and polymorphism.

Heptane is a suitable solvent for these processes because it has a low polarity, a low toxicity, a high volatility, and a good compatibility with other solvents. Heptane can dissolve or extract the APIs from the impurities, such as water, salts, sugars, proteins, and other organic compounds. Heptane can also be used to recrystallize the APIs by changing the temperature, the concentration, or the addition of other solvents. Heptane can be easily removed from the APIs by evaporation, filtration, or centrifugation, leaving behind a dry and pure solid.

Some examples of APIs that are extracted, purified, or crystallized with heptane are:

  • Aspirin, an anti-inflammatory and analgesic drug that is synthesized from salicylic acid and acetic anhydride. Heptane is used to wash and dry the crude aspirin crystals, and then to recrystallize them with ethanol.
  • Ibuprofen, an anti-inflammatory and analgesic drug that is synthesized from isobutylbenzene and propionic acid. Heptane is used to extract the ibuprofen from the reaction mixture, and then to recrystallize it with ethanol or acetone.
  • Paracetamol, an analgesic and antipyretic drug that is synthesized from phenol and acetic anhydride. Heptane is used to extract the paracetamol from the reaction mixture, and then to recrystallize it with water or ethanol.
  • Caffeine, a stimulant and diuretic drug that is derived from coffee beans or tea leaves. Heptane is used to extract the caffeine from the raw materials, and then to recrystallize it with water or ethanol.

Pharmaceutical-grade heptane is an important solvent for the production of APIs, as it can ensure the quality, safety, and efficacy of the drugs. However, heptane also has some drawbacks, such as its flammability, its environmental impact, and its potential health hazards. Therefore, heptane has to be handled with care and disposed of properly, following the regulations and guidelines of the authorities and the industry.

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