n-Heptane Overview
n-Heptane (CAS No. 142-82-5, EC No. 205-563-8) is a straight-chain hydrocarbon (C₇H₁₆) recognized throughout the European regulatory framework as a key industrial solvent. It is classified under the CLP Regulation Annex VI and officially registered in ECHA’s Registered Substances Database, confirming its full REACH compliance for import and use across the European Economic Area (EEA) at volumes exceeding 1,000 tonnes per year.
Substance Names and Other Identifiers
Main substance name:
Other common names and synonyms:
- Heptane
- Heptan
- Heptanen
- Dipropylmethane
- Dipropyl methane
- Heptyl hydride
- Normal heptane
- Heptane (all isomers)
- Heptane [99.0% for HPLC Solvent]
- Heptane [and isomers]
- n-Heptano
- Gettysolve-C
- Skellysolve C
- Eptani
- Hydrocarbon solvents
Regulatory process names:
- Heptane
- Heptane; n-Heptane
- n-Heptane
- heptane/n-heptane
Translated names (examples):
- Heptan, n-Heptan (German)
- Heptan, N-heptan (Romanian)
Trade names:
Identifiers:
- CAS number: 142-82-5
- EC number: 205-563-8
- Index number: 601-008-00-2
- Other CAS numbers (legacy or related): 44607-13-8, 8031-33-2
IUPAC names:
- Dipropylmethane
- n-Heptane
Regulatory and Directive references:
n-Heptane is listed under multiple EU regulations and directives, including:
General Product Safety Regulation – Hazardous Substances
REACH Registration Dossier
EC Inventory
C&L Inventory
Pre-registration process
Aerosols Directive – Flammable Contents
Chemical Agents Directive (CAD) – Hazardous Agents
Ambient Air Quality Directive, Annex X – Ozone Precursor Substances
Occupational Exposure Limits (OELVs) – Indicative List
Construction Products Regulation – Hazardous Substances (Annex I & Art. 6)
EU Ecolabel Regulation – Hazardous Substance Restrictions
Medical Devices Directives and Regulations – Hazardous Substances
Pressure Equipment Directive – Group 1 Fluids
Waste Framework Directive – Annex III Hazardous Properties
Fertiliser Regulation, Annex I, E.3 – Chelating/Complexing Agents
Due to its extensive industrial and scientific use, n-Heptane is known under a wide range of regulatory, IUPAC, and trade names across different European legislations and databases.
Regulatory Process Names:
Dipropyl Methane, Eptani, Gettysolve-C, Heptan, Heptane, Heptanen, Heptyl Hydride, n-Heptane, Skellysolve C
Translated Names (EU languages):
- Heptan / n-Heptan (DE) – German
- Heptan / N-heptan (RO) – Romanian
IUPAC and Technical Names:
Dipropylmethane, n-Heptane, Heptane (all isomers), Heptane [99.0% for HPLC Solvent], Normal Heptane, Hydrocarbon Solvent
Trade Names:
Heptane, n-Heptane, Gettysolve-C, Skellysolve C
Identifiers:
- CAS Number: 142-82-5 (Main)
- EC Number: 205-563-8
- Index Number (CLP): 601-008-00-2
- Other CAS Numbers: 44607-13-8, 8031-33-2
- Molecular Formula: C₇H₁₆
These identifiers appear consistently across EINECS, C&L Inventory, REACH Pre-registration, and multiple EU regulatory annexes, ensuring full traceability and transparency in supply.
Regulatory Framework and Compliance
n-Heptane is explicitly listed under numerous European chemical and environmental legislations, highlighting its regulated yet accepted status in industrial and laboratory operations:
- REACH Regulation – Registered substance (≥1000 tpa)
- CLP Regulation Annex VI – Harmonized classification & labeling
- Seveso III Directive Annex I – Industrial accident prevention
- Waste Framework Directive Annex III – Hazardous properties
- Occupational Exposure Limits (OELs) – Indicative EU OELVs
- Construction Products Regulation (Annex I & Art.6(5))
- EU Ecolabels & Environmental Policy Framework Directive
- Medical Devices Regulation / Directive (Hazardous Substances)
- General Product Safety Regulation & Workplace Safety Directive
This extensive inclusion across directives confirms that n-Heptane is both recognized and regulated for controlled industrial use, making it an ideal choice for European manufacturers seeking long-term compliant sourcing.
Applications Across European Industries
n-Heptane’s versatility has established it as a critical raw material and process solvent in:
- Pharmaceutical manufacturing – extraction, crystallization, and purification
- Laboratories – high-purity analytical use (HPLC, GC)
- Coatings and adhesives – solvent and viscosity control
- Automotive and fuel industry – reference standard for octane rating
- Cleaning and degreasing agents – controlled volatility applications
Safety and Environmental Management
Classified as a highly flammable liquid (H225), skin irritant (H315), and toxic to aquatic life (H410), n-Heptane must be handled with professional containment, proper labeling, and full compliance to the GHS/CLP system.
Manufacturers provide complete Safety Data Sheets (SDS) and Guidance on Safe Use, aligned with the Chemical Agents Directive (CAD) and Pressure Equipment Directive.
Why Choose Our n-Heptane
Fully REACH-registered and CLP compliant
High-purity grades (up to 99%) for pharmaceutical and analytical use
Stable European supply in ISO tanks or drums
Complete documentation package (SDS, COA, technical data)
Proven compliance with EU industrial, medical, and environmental standards
Our n-Heptane product line delivers consistency, safety, and full regulatory transparency for European customers in pharmaceuticals, R&D, and specialty chemicals manufacturing.
For technical details, safety classifications, and compliance information, professionals can refer to the European Chemicals Agency (ECHA) official database:
https://echa.europa.eu/substance-information/-/substanceinfo/100.014.194
This authoritative link strengthens data transparency and helps industry experts verify REACH registration status, CLP classification, and exposure limits of n-Heptane (CAS 142-82-5) under European regulatory frameworks.