Archives October 8, 2025

— Supporting High-Standard Compliance in the Pharmaceutical Industry

We are pleased to announce that our n-Heptane (CAS No.: 142-82-5) has successfully obtained EU REACH 1000MT+ registration, marking a significant step forward in regulatory compliance, safety, and market access. This achievement highlights our commitment to regulatory excellence and sustainable supply in the global chemical market.

Applications of n-Heptane in the Pharmaceutical Industry

In the pharmaceutical sector, n-Heptane is an essential organic solvent widely used across analysis, purification, and formulation development. Its non-polar nature and high purity make it an ideal choice in various drug manufacturing processes:

• Solvent Functions: Used for extraction, crystallization, and separation processes, particularly effective in purifying active pharmaceutical ingredients (APIs) or intermediates.
• Chromatographic Analysis: Serves as a standard solvent for gas chromatography (GC) or high-performance liquid chromatography (HPLC), facilitating accurate analysis of drug components and impurities.
• Formulation Development: Acts as an excipient or process solvent in certain formulations, assisting coating, granulation, and drying processes.
• Cleaning Agent: Suitable for cleaning equipment or glassware, especially in water-sensitive production processes.
• Reference Material: Employed in pharmacopeial testing as a standard for instrument calibration or method validation.

Significance of REACH Registration

REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) is one of the strictest chemical regulatory frameworks worldwide. Achieving 1000MT+ registration allows us to legally supply over 1,000 tons of n-Heptane annually to the EU market, backed by comprehensive physical-chemical, toxicological, and environmental assessments.

This milestone reflects our dedication to quality and regulatory compliance while strengthening our competitive edge across the pharmaceutical, coatings, rubber, ink, and specialty chemical industries.

Safety and Compliance

n-Heptane is volatile and possesses neurotoxic potential. It should be handled in well-ventilated areas with appropriate protective measures. We uphold the principles of safety, environmental responsibility, and regulatory compliance to provide customers with high-standard chemical solutions and technical support.

For technical data sheets (TDS), MSDS, or regulatory support documents related to n-Heptane, please feel free to contact us.

#Heptane #nHeptane #REACH #PharmaceuticalSolvent #GreenChemistry #ChemicalCompliance

In pharmaceutical manufacturing, purity is more than a specification — it’s a promise. Every solvent plays a critical role in ensuring product safety, consistency, and regulatory compliance. That’s why we’re proud to introduce our premium-grade n-Heptane, produced by the only REACH-registered manufacturer in China.

Why Choose Our n-Heptane

• REACH-Certified for Europe We are the sole Chinese producer of n-Heptane officially registered under the EU REACH regulation. This guarantees full compliance for import and use across European markets, including Italy.
• Pharmaceutical-Grade Purity With purity levels exceeding 99%, our n-Heptane meets the stringent requirements of pharmaceutical applications — from active ingredient extraction to crystallization and cleaning processes.
• Reliable Supply and Documentation We offer consistent production capacity, flexible packaging options, and complete technical documentation including COA and MSDS, ensuring smooth procurement and regulatory alignment.
• Dedicated Support for European Clients Our experienced export team provides clear communication, fast response times, and full assistance with logistics coordination and compliance paperwork.

Bridging Chinese Manufacturing with European Standards

Our REACH certification is more than a regulatory milestone — it’s a symbol of our long-term commitment to quality, safety, and partnership. We understand the expectations of European pharmaceutical companies and deliver accordingly.

Let’s Build a Smarter, Safer Supply Chain Together

Whether you’re optimizing your sourcing strategy or seeking a more compliant and cost-effective alternative, our n-Heptane is ready to meet your needs.

n-Heptane (CAS No.: 142-82-5) is a widely used non-polar organic solvent in pharmaceuticals, coatings, and specialty chemical industries. While its high purity and versatile applications make it an essential industrial chemical, it is important to understand its flash point, a critical property for safe handling and storage.

What is Flash Point?

The flash point of a liquid is the lowest temperature at which it can vaporize to form a combustible mixture with air. At or above this temperature, a spark or flame can ignite the vapor, potentially causing fire or explosion. Understanding flash points is fundamental for classifying chemicals, selecting storage conditions, and implementing safety measures.

Flash Point of n-Heptane

n-Heptane is highly flammable, with a flash point of approximately −4°C (24.8°F). This extremely low value indicates that n-Heptane can easily form flammable vapors at room temperature, emphasizing the need for caution during handling.

Safety Implications

Because of its low flash point, n-Heptane requires careful handling to minimize fire hazards:

• Storage: Keep in tightly sealed containers, away from heat, sparks, and open flames.
• Ventilation: Use in well-ventilated areas to prevent vapor accumulation.
• Personal Protection: Wear flame-resistant clothing and appropriate gloves and goggles.
• Grounding and Bonding: When transferring n-Heptane between containers, ensure proper grounding to avoid static sparks.

Industrial Relevance

Understanding n-Heptane’s flash point is not only important for laboratory and industrial safety but also for regulatory compliance. It helps chemical manufacturers, distributors, and end-users comply with fire safety regulations, REACH guidelines, and occupational health standards.

Conclusion

The flash point of n-Heptane is a key physical property that underscores its high flammability. Proper knowledge, storage, and handling practices ensure that this versatile solvent can be safely used in pharmaceutical, coating, and specialty chemical applications.

#nHeptane #Heptane #ChemicalSafety #FlashPoint #PharmaceuticalSolvent #FlammableLiquids #ChemicalCompliance

At Junyuan Petroleum Group’s flagship facility, our newly commissioned alkane adsorption separation unit is now delivering 99.9% ultra-high-purity n-Hexane—a pharmaceutical-grade intermediate essential for precision synthesis. Its exceptional chemical stability minimizes side reactions, enabling tighter control over drug yields and manufacturing consistency.

Since first commercializing n-Hexane with >99.6% purity in December 2006, Junyuan has continuously advanced its production capabilities. As of August 2025, we’ve become China’s first petroleum-based producer of ultra-high-purity n-Hexane, replacing imported alternatives and setting new standards for domestic chemical manufacturing.

This breakthrough reflects Junyuan’s enduring commitment to innovation in energy and fine chemicals—where purity, reliability, and performance are mission-critical.

Follow Junyuan Petroleum Group for more milestones in precision engineering and industrial excellence.