Archives October 2025

Product Overview

n-Heptane 99% is a high-purity aliphatic hydrocarbon solvent widely used in pharmaceutical synthesis, analytical testing, and specialty chemical manufacturing. With its narrow distillation range, low aromatic content, and excellent volatility characteristics, it ensures consistency and reliability in every application.

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Technical Specifications

Parameter	Specification
Density (15°C, g/cm³)	0.685 – 0.693
Appearance	Clear and colorless
Water Content (ppm)	≤ 50
Saybolt Color	≥ +30
Copper Corrosion (100°C, 2h)	≤ 1
Non-volatile Residue (mg/100ml)	≤ 1
Refractive Index (20°C)	1.3870 – 1.3890
Aromatic Content (ppm)	≤ 10
Benzene Content (ppm)	≤ 2
Sulfur Content (ppm)	≤ 1
Purity (% m/m)	≥ 99
3-Methylhexane (%)	≤ 0.50
2-Methylhexane (%)	≤ 0.20
Methylcyclohexane (%)	≤ 0.30
Initial Boiling Point (IBP, °C)	≥ 96
Final Boiling Point (DP, °C)	≤ 105
Distillation Range (5–95%, °C)	≤ 1.5

These specifications demonstrate excellent batch consistency, low impurity levels, and high solvent performance, ensuring suitability for critical manufacturing environments.

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Compliance and Safety Statements

Melamine-Free Statement
No melamine is used during production, and the product contains no melamine residues.

Nitrosamines-Free Statement
n-Heptane is a pure hydrocarbon solvent. No nitrosamine compounds are introduced or present in the product.

Absence of Glycols
This product contains no glycol components.

Absence of Mesylates (Methanesulfonates)
n-Heptane production does not involve any sulfonate compounds; mesylates are confirmed absent.

Genotoxic Impurities Statement
n-Heptane is a single-component hydrocarbon solvent and does not contain any genotoxic impurities.

Absence of Allergens, Aflatoxins, and Additives
Derived from petroleum hydrocarbon distillates, n-Heptane is produced without the addition of allergens, aflatoxins, or food/pharmaceutical additives.

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Key Advantages

• High purity (≥99%) for sensitive chemical and pharmaceutical processes
• Extremely low aromatic and sulfur content, ensuring clean performance
• Stable physicochemical properties across production batches
• Fully compliant with industry safety and purity expectations

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Applications

• Pharmaceuticals: Extraction, crystallization, and purification
• Fine Chemicals: Reaction solvent and intermediate carrier
• Analytical Laboratories: Chromatographic analysis and sample preparation
• Coatings & Adhesives: Formulation of high-performance systems requiring non-polar solvents

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Conclusion

n-Heptane 99% is a premium-grade hydrocarbon solvent that meets the stringent technical and regulatory requirements of modern industries. With consistent purity, verified compliance, and reliable global supply, it is an ideal choice for manufacturers seeking efficiency, safety, and performance in solvent applications.

Purpose of Sulfiding a Catalyst

In petroleum refining and petrochemical processes, sulfiding is the essential activation step for hydrotreating (HDS), hydrodesulfurization (HDS), hydrodenitrogenation (HDN), and hydrocracking catalysts that contain nickel (Ni), cobalt (Co), and molybdenum (Mo) or tungsten (W) on alumina.

Fresh catalysts are typically in their oxide form (NiO, CoO, MoO₃, etc.), which are inactive for removing sulfur, nitrogen, or metals.
Sulfiding converts these oxides into active sulfide phases such as:

• Ni₃S₂
• Co₉S₈
• MoS₂
• WS₂

These metal sulfides are the true active sites that drive hydrodesulfurization and hydrogenation reactions.

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Role of DTBPS (Di-tert-Butyl Polysulfide)

DTBPS is a liquid sulfiding agent used to pre-sulfide or in-situ sulfide hydrotreating catalysts in a controlled, safe, and efficient way.

Key points:

• Chemical formula: (t-C₄H₉)₂Sₓ (x ≈ 2–5)
• Sulfur content: ~54–58%
• Boiling range: around 220–300 °C
• Flash point: high, making it safer to handle than H₂S or dimethyl disulfide (DMDS)

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How DTBPS Works

When DTBPS is introduced into the reactor (usually co-fed with hydrogen and a hydrocarbon solvent), it decomposes gradually at moderate temperatures (around 200–350 °C) to release sulfur species (H₂S and organosulfur intermediates).

These sulfur species react with the metal oxides on the catalyst to form the desired sulfide phases: MOx+H2S→MS+H2OMO_x + H_2S → MS + H_2OMOx​+H2​S→MS+H2​O

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Advantages of DTBPS

✅ Safer than DMDS (less toxic, less volatile, higher flash point)
✅ Controlled sulfur release, minimizing temperature runaway
✅ Cleaner operation — less odor and corrosion
✅ No need for external H₂S injection
✅ Compatible with various refinery units — hydrotreaters, hydrocrackers, reforming pretreatment

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In Summary

Aspect	DTBPS Function / Benefit
Main Purpose	Converts oxide catalyst to active sulfide form
Active Sulfur Source	Releases H₂S in situ
Typical Use	Start-up or activation of NiMo, CoMo, NiW catalysts
Benefit	Safe, efficient, and environmentally friendly sulfiding

Certificate of Analysis (COA)
Product Name: Cyclopentane/Isopentane Blend (80-20%)
Batch No.: JY20251014
Date of Manufacture: October 14, 2025
Date of Analysis: October 14, 2025
Manufacturer: Junyuan Petroleum Group
Packaging Type: ISO Tank
Quantity: 16 Metric Tons

Analytical Results:

Parameter	Specification Range	Test Result	Unit	Test Method
Cyclopentane Content	78.0 – 82.0	80.3	wt%	GC
Isopentane Content	18.0 – 22.0	19.7	wt%	GC
Total Sulfur	≤ 5	2.1	ppm	ASTM D5453
Benzene Content	≤ 5	1.3	ppm	GC-MS

Application:

This product is primarily used as a blowing agent in the production of polyurethane foams, especially for refrigeration insulation panels and construction-grade thermal insulation materials. It may also be used as a solvent or formulation component in chemical manufacturing processes requiring low boiling point hydrocarbons.

Remarks:

• All values are based on standard laboratory testing procedures.
• The product meets the required specifications and is suitable for industrial use.
• This COA is issued by the Quality Control Department and reflects the actual batch performance.

1. Product Overview

Cyclopentane (Low Thermal Conductivity Type) is a high-efficiency hydrocarbon blowing agent developed for polyurethane (PU) rigid foam insulation systems. Compared with traditional blowing agents, it provides superior insulation performance, environmental protection, and process safety. It is an ideal alternative to CFC and HCFC agents, aligning with global environmental trends.

Main advantages include:

low thermal conductivity for enhanced insulation efficiency;

zero ozone depletion potential (ODP = 0);

low global warming potential (GWP);

and stable, safe, and efficient supply and transportation.

2. Technical Advantages

First, its low thermal conductivity delivers excellent insulation performance. The product’s optimized molecular design and uniform foam-cell structure help reduce heat transfer, significantly improving the thermal insulation capacity of polyurethane foam. It has been successfully used in refrigerators, freezers, and construction panels to help products achieve higher energy efficiency standards.

Second, it offers outstanding environmental compatibility. Cyclopentane contains no chlorine or fluorine and therefore has zero ozone depletion potential. Its greenhouse gas impact is minimal, and it meets the latest global environmental protection regulations. The product supports industries in achieving sustainability and carbon reduction targets.

Third, it is cost-effective and highly compatible with existing foaming processes. Raw materials are abundant, production technology is mature, and it can directly replace traditional systems without major equipment modifications. Compared with imported fluorinated blowing agents, it offers more stable costs and shorter delivery times.

Fourth, it ensures operational safety when handled properly. As a flammable hydrocarbon, Cyclopentane should be used in well-ventilated, explosion-proof environments. Standardized closed systems, anti-static measures, and professional storage and transportation management can effectively minimize risks. Industrial users have already accumulated mature experience in its safe and stable application.

3. Application Fields

Cyclopentane (Low Thermal Conductivity Type) is suitable for a wide range of polyurethane rigid foam applications that require both high insulation and environmental performance.

In the household appliance sector, it is mainly used as a blowing agent in refrigerator and freezer insulation systems, improving energy efficiency and reducing power consumption.

In the building materials sector, it is widely used in wall and roof insulation panels. Its low thermal conductivity helps buildings meet increasingly strict energy-saving standards.

In the cold chain and logistics sector, it is used in the insulation layers of refrigerated trucks and cold storage equipment, effectively reducing heat loss and improving temperature stability.

In the industrial sector, it is used for the insulation of pipes, tanks, and other equipment that require long-term thermal stability and durable foam structures.

The product formulation can be customized to meet different application requirements, ensuring consistent performance across diverse foaming systems.

4. Market Potential

With the global elimination of fluorinated blowing agents, hydrocarbon-based alternatives are gaining rapid adoption. Cyclopentane (Low Thermal Conductivity Type) has become one of the most promising options thanks to its combination of high energy efficiency, low environmental impact, cost-effectiveness, and reliable availability.

Under the global carbon neutrality trend, demand for sustainable insulation materials continues to rise. Cyclopentane (Low Thermal Conductivity Type) will play a vital role in next-generation insulation systems for refrigeration, construction, and industrial applications.

5. Promotional Summary

Cyclopentane (Low Thermal Conductivity Type) — Smarter Insulation, Greener Future.

Engineered for superior thermal efficiency and environmental protection.

Low thermal conductivity, zero ODP, low GWP, stable and cost-effective performance.

Ideal for energy-efficient refrigerators, building insulation panels, and cold-chain logistics.

Lower conductivity. Higher sustainability.

— Supporting High-Standard Compliance in the Pharmaceutical Industry

We are pleased to announce that our n-Heptane (CAS No.: 142-82-5) has successfully obtained EU REACH 1000MT+ registration, marking a significant step forward in regulatory compliance, safety, and market access. This achievement highlights our commitment to regulatory excellence and sustainable supply in the global chemical market.

Applications of n-Heptane in the Pharmaceutical Industry

In the pharmaceutical sector, n-Heptane is an essential organic solvent widely used across analysis, purification, and formulation development. Its non-polar nature and high purity make it an ideal choice in various drug manufacturing processes:

• Solvent Functions: Used for extraction, crystallization, and separation processes, particularly effective in purifying active pharmaceutical ingredients (APIs) or intermediates.
• Chromatographic Analysis: Serves as a standard solvent for gas chromatography (GC) or high-performance liquid chromatography (HPLC), facilitating accurate analysis of drug components and impurities.
• Formulation Development: Acts as an excipient or process solvent in certain formulations, assisting coating, granulation, and drying processes.
• Cleaning Agent: Suitable for cleaning equipment or glassware, especially in water-sensitive production processes.
• Reference Material: Employed in pharmacopeial testing as a standard for instrument calibration or method validation.

Significance of REACH Registration

REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) is one of the strictest chemical regulatory frameworks worldwide. Achieving 1000MT+ registration allows us to legally supply over 1,000 tons of n-Heptane annually to the EU market, backed by comprehensive physical-chemical, toxicological, and environmental assessments.

This milestone reflects our dedication to quality and regulatory compliance while strengthening our competitive edge across the pharmaceutical, coatings, rubber, ink, and specialty chemical industries.

Safety and Compliance

n-Heptane is volatile and possesses neurotoxic potential. It should be handled in well-ventilated areas with appropriate protective measures. We uphold the principles of safety, environmental responsibility, and regulatory compliance to provide customers with high-standard chemical solutions and technical support.

For technical data sheets (TDS), MSDS, or regulatory support documents related to n-Heptane, please feel free to contact us.

#Heptane #nHeptane #REACH #PharmaceuticalSolvent #GreenChemistry #ChemicalCompliance

In pharmaceutical manufacturing, purity is more than a specification — it’s a promise. Every solvent plays a critical role in ensuring product safety, consistency, and regulatory compliance. That’s why we’re proud to introduce our premium-grade n-Heptane, produced by the only REACH-registered manufacturer in China.

Why Choose Our n-Heptane

• REACH-Certified for Europe We are the sole Chinese producer of n-Heptane officially registered under the EU REACH regulation. This guarantees full compliance for import and use across European markets, including Italy.
• Pharmaceutical-Grade Purity With purity levels exceeding 99%, our n-Heptane meets the stringent requirements of pharmaceutical applications — from active ingredient extraction to crystallization and cleaning processes.
• Reliable Supply and Documentation We offer consistent production capacity, flexible packaging options, and complete technical documentation including COA and MSDS, ensuring smooth procurement and regulatory alignment.
• Dedicated Support for European Clients Our experienced export team provides clear communication, fast response times, and full assistance with logistics coordination and compliance paperwork.

Bridging Chinese Manufacturing with European Standards

Our REACH certification is more than a regulatory milestone — it’s a symbol of our long-term commitment to quality, safety, and partnership. We understand the expectations of European pharmaceutical companies and deliver accordingly.

Let’s Build a Smarter, Safer Supply Chain Together

Whether you’re optimizing your sourcing strategy or seeking a more compliant and cost-effective alternative, our n-Heptane is ready to meet your needs.

n-Heptane (CAS No.: 142-82-5) is a widely used non-polar organic solvent in pharmaceuticals, coatings, and specialty chemical industries. While its high purity and versatile applications make it an essential industrial chemical, it is important to understand its flash point, a critical property for safe handling and storage.

What is Flash Point?

The flash point of a liquid is the lowest temperature at which it can vaporize to form a combustible mixture with air. At or above this temperature, a spark or flame can ignite the vapor, potentially causing fire or explosion. Understanding flash points is fundamental for classifying chemicals, selecting storage conditions, and implementing safety measures.

Flash Point of n-Heptane

n-Heptane is highly flammable, with a flash point of approximately −4°C (24.8°F). This extremely low value indicates that n-Heptane can easily form flammable vapors at room temperature, emphasizing the need for caution during handling.

Safety Implications

Because of its low flash point, n-Heptane requires careful handling to minimize fire hazards:

• Storage: Keep in tightly sealed containers, away from heat, sparks, and open flames.
• Ventilation: Use in well-ventilated areas to prevent vapor accumulation.
• Personal Protection: Wear flame-resistant clothing and appropriate gloves and goggles.
• Grounding and Bonding: When transferring n-Heptane between containers, ensure proper grounding to avoid static sparks.

Industrial Relevance

Understanding n-Heptane’s flash point is not only important for laboratory and industrial safety but also for regulatory compliance. It helps chemical manufacturers, distributors, and end-users comply with fire safety regulations, REACH guidelines, and occupational health standards.

Conclusion

The flash point of n-Heptane is a key physical property that underscores its high flammability. Proper knowledge, storage, and handling practices ensure that this versatile solvent can be safely used in pharmaceutical, coating, and specialty chemical applications.

#nHeptane #Heptane #ChemicalSafety #FlashPoint #PharmaceuticalSolvent #FlammableLiquids #ChemicalCompliance

At Junyuan Petroleum Group’s flagship facility, our newly commissioned alkane adsorption separation unit is now delivering 99.9% ultra-high-purity n-Hexane—a pharmaceutical-grade intermediate essential for precision synthesis. Its exceptional chemical stability minimizes side reactions, enabling tighter control over drug yields and manufacturing consistency.

Since first commercializing n-Hexane with >99.6% purity in December 2006, Junyuan has continuously advanced its production capabilities. As of August 2025, we’ve become China’s first petroleum-based producer of ultra-high-purity n-Hexane, replacing imported alternatives and setting new standards for domestic chemical manufacturing.

This breakthrough reflects Junyuan’s enduring commitment to innovation in energy and fine chemicals—where purity, reliability, and performance are mission-critical.

Follow Junyuan Petroleum Group for more milestones in precision engineering and industrial excellence.

With the rapid development of European industry and increasingly strict environmental standards, the demand for high-quality n-Heptane continues to rise. Starting in 2025, Junyuan Petroleum Group, a global leading n-Heptane producer, has officially entered the European market with its REACH certified products, providing reliable, high-purity, and eco-friendly solutions for the pharmaceutical, electronics, coatings, and chemical industries.

Market Opportunities and Trends

The European n-Heptane market is growing rapidly, particularly in pharmaceuticals, automotive, coatings, and electronics, where high-purity (≥99%) and eco-friendly n-Heptane is increasingly required. Despite limited local production and closures of major facilities, Junyuan Petroleum Group’s entry effectively addresses supply gaps, offering stable supply to customers.

Key Applications

• Pharmaceuticals: High-purity n-Heptane is used in drug synthesis, formulation, and chromatography purification.
• Automotive: Solvent for coatings, adhesives, and fuel additives.
• Coatings & Paints: Quick evaporation and strong solvency ensure smooth surfaces.
• Chemicals & Electronics: Used in specialty chemicals, lubricants, and component cleaning.
• Food & Beverage: Extraction and purification of natural flavors and essential oils.

European Market Highlights

• Western Europe Dominance: Germany, France, and the UK have stable industrial demand.
• Emerging Eastern Europe: Poland, Hungary, and the Czech Republic show high growth potential.
• Sustainability Focus: REACH certification is a key market entry requirement, and Europe emphasizes green chemistry.

Strategic Advantage of Junyuan Petroleum Group

Through global production and mature technology, Junyuan Petroleum Group provides high-purity, eco-friendly, and stable supply of n-Heptane, meeting the strict standards of European clients. With full REACH certification since 2025, the n-Heptane market in Europe is poised for comprehensive growth.

Abstract:
n-Heptane (CAS 142-82-5; EC 205-563-8) is a registered substance under the European Union’s REACH regulation, enabling its safe and compliant use across diverse industries. As a mono-constituent substance of petroleum origin, n-Heptane is registered for tonnage bands exceeding 1,000 tonnes per year, ensuring wide availability for European buyers. The REACH registration dossier highlights its extensive applications, including as a solvent in manufacturing, a fuel additive, a component in coatings and adhesives, and in laboratory processes. Businesses sourcing n-Heptane in the EU should request REACH certificates, Safety Data Sheets (SDS), and confirmation of tonnage coverage from suppliers to guarantee regulatory compliance. For downstream users, verifying that specific applications are covered in the supplier’s dossier is crucial, while importers must ensure valid registration via their EU-based entity or Only Representative. With its robust regulatory framework and versatile uses, n-Heptane is positioned as a reliable, compliant, and high-value solvent and process material in the European market.

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n-Heptane and REACH Registration in the EU

n-Heptane has been successfully registered under the EU’s REACH regulation (Registration, Evaluation, Authorisation and Restriction of Chemicals). The registration process ensures that the substance complies with stringent European standards for safety, environmental impact, and responsible use.

• Identifiers:
  • CAS Number: 142-82-5
  • EC Number: 205-563-8
  • Typical Registration Number Format: 01-2119457603-38-xxxx
• Substance Type:
  n-Heptane is registered as a mono-constituent substance, most commonly of petroleum origin.
• Tonnage Band:
  Registrations cover >1,000 tonnes per year, reflecting its broad industrial demand.

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Industrial Applications of n-Heptane

The versatility of n-Heptane makes it an essential material across multiple European industries. Key applications include:

• Solvent in manufacturing processes – widely used in adhesives, coatings, and extraction processes.
• Fuel and fuel additives – supporting clean combustion and blending.
• Cleaning agents – valued for its efficiency in dissolving oils and greases.
• Laboratory applications – as a reference solvent and calibration standard.
• Formulations – incorporated into paints, coatings, and industrial adhesives.

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Compliance Documentation for Buyers

To ensure smooth operations and full compliance, buyers in the EU should request the following documents from suppliers:

1. REACH Certificate – official proof that the product is registered under REACH.
2. Safety Data Sheet (SDS) – including the REACH registration number and hazard/safety guidance.
3. Confirmation of Tonnage Coverage – assurance that the supplier’s registration covers the required quantity and intended use.

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Obligations for Buyers in the EU

• Downstream Users:
  Businesses that use n-Heptane in production must confirm that their applications are included in the supplier’s registration dossier. The SDS will provide this detail.
• Importers:
  If n-Heptane is imported from outside the EU, the responsibility for REACH registration lies with the importer. Alternatively, the non-EU manufacturer can appoint an “Only Representative” to manage registration on their behalf. In both cases, importers should obtain the valid REACH registration number.

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Conclusion

With full REACH registration, n-Heptane is a reliable and compliant material for European industries. Its wide-ranging applications, regulatory approval, and high-volume availability position it as a critical solvent and process chemical. By sourcing from trusted suppliers and ensuring the proper documentation, buyers can secure both regulatory compliance and uninterrupted supply.

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Keywords:
n-Heptane, REACH compliance, European market, solvent, coatings, adhesives, fuel additive, laboratory applications, CAS 142-82-5, EC 205-563-8