Tag REACH

n-Heptane Overview

n-Heptane (CAS No. 142-82-5, EC No. 205-563-8) is a straight-chain hydrocarbon (C₇H₁₆) recognized throughout the European regulatory framework as a key industrial solvent. It is classified under the CLP Regulation Annex VI and officially registered in ECHA’s Registered Substances Database, confirming its full REACH compliance for import and use across the European Economic Area (EEA) at volumes exceeding 1,000 tonnes per year.

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Substance Names and Other Identifiers

Main substance name:

• n-Heptane

Other common names and synonyms:

• Heptane
• Heptan
• Heptanen
• Dipropylmethane
• Dipropyl methane
• Heptyl hydride
• Normal heptane
• Heptane (all isomers)
• Heptane [99.0% for HPLC Solvent]
• Heptane [and isomers]
• n-Heptano
• Gettysolve-C
• Skellysolve C
• Eptani
• Hydrocarbon solvents

Regulatory process names:

• Heptane
• Heptane; n-Heptane
• n-Heptane
• heptane/n-heptane

Translated names (examples):

• Heptan, n-Heptan (German)
• Heptan, N-heptan (Romanian)

Trade names:

• Heptane
• n-Heptane

Identifiers:

• CAS number: 142-82-5
• EC number: 205-563-8
• Index number: 601-008-00-2
• Other CAS numbers (legacy or related): 44607-13-8, 8031-33-2

IUPAC names:

• Dipropylmethane
• n-Heptane

Regulatory and Directive references:
n-Heptane is listed under multiple EU regulations and directives, including:

General Product Safety Regulation – Hazardous Substances

REACH Registration Dossier

EC Inventory

C&L Inventory

Pre-registration process

Aerosols Directive – Flammable Contents

Chemical Agents Directive (CAD) – Hazardous Agents

Ambient Air Quality Directive, Annex X – Ozone Precursor Substances

Occupational Exposure Limits (OELVs) – Indicative List

Construction Products Regulation – Hazardous Substances (Annex I & Art. 6)

EU Ecolabel Regulation – Hazardous Substance Restrictions

Medical Devices Directives and Regulations – Hazardous Substances

Pressure Equipment Directive – Group 1 Fluids

Waste Framework Directive – Annex III Hazardous Properties

Fertiliser Regulation, Annex I, E.3 – Chelating/Complexing Agents

Due to its extensive industrial and scientific use, n-Heptane is known under a wide range of regulatory, IUPAC, and trade names across different European legislations and databases.

Regulatory Process Names:
Dipropyl Methane, Eptani, Gettysolve-C, Heptan, Heptane, Heptanen, Heptyl Hydride, n-Heptane, Skellysolve C

Translated Names (EU languages):

• Heptan / n-Heptan (DE) – German
• Heptan / N-heptan (RO) – Romanian

IUPAC and Technical Names:
Dipropylmethane, n-Heptane, Heptane (all isomers), Heptane [99.0% for HPLC Solvent], Normal Heptane, Hydrocarbon Solvent

Trade Names:
Heptane, n-Heptane, Gettysolve-C, Skellysolve C

Identifiers:

• CAS Number: 142-82-5 (Main)
• EC Number: 205-563-8
• Index Number (CLP): 601-008-00-2
• Other CAS Numbers: 44607-13-8, 8031-33-2
• Molecular Formula: C₇H₁₆

These identifiers appear consistently across EINECS, C&L Inventory, REACH Pre-registration, and multiple EU regulatory annexes, ensuring full traceability and transparency in supply.

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Regulatory Framework and Compliance

n-Heptane is explicitly listed under numerous European chemical and environmental legislations, highlighting its regulated yet accepted status in industrial and laboratory operations:

• REACH Regulation – Registered substance (≥1000 tpa)
• CLP Regulation Annex VI – Harmonized classification & labeling
• Seveso III Directive Annex I – Industrial accident prevention
• Waste Framework Directive Annex III – Hazardous properties
• Occupational Exposure Limits (OELs) – Indicative EU OELVs
• Construction Products Regulation (Annex I & Art.6(5))
• EU Ecolabels & Environmental Policy Framework Directive
• Medical Devices Regulation / Directive (Hazardous Substances)
• General Product Safety Regulation & Workplace Safety Directive

This extensive inclusion across directives confirms that n-Heptane is both recognized and regulated for controlled industrial use, making it an ideal choice for European manufacturers seeking long-term compliant sourcing.

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Applications Across European Industries

n-Heptane’s versatility has established it as a critical raw material and process solvent in:

• Pharmaceutical manufacturing – extraction, crystallization, and purification
• Laboratories – high-purity analytical use (HPLC, GC)
• Coatings and adhesives – solvent and viscosity control
• Automotive and fuel industry – reference standard for octane rating
• Cleaning and degreasing agents – controlled volatility applications

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Safety and Environmental Management

Classified as a highly flammable liquid (H225), skin irritant (H315), and toxic to aquatic life (H410), n-Heptane must be handled with professional containment, proper labeling, and full compliance to the GHS/CLP system.
Manufacturers provide complete Safety Data Sheets (SDS) and Guidance on Safe Use, aligned with the Chemical Agents Directive (CAD) and Pressure Equipment Directive.

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Why Choose Our n-Heptane

Fully REACH-registered and CLP compliant
High-purity grades (up to 99%) for pharmaceutical and analytical use
Stable European supply in ISO tanks or drums
Complete documentation package (SDS, COA, technical data)
Proven compliance with EU industrial, medical, and environmental standards

Our n-Heptane product line delivers consistency, safety, and full regulatory transparency for European customers in pharmaceuticals, R&D, and specialty chemicals manufacturing.

For technical details, safety classifications, and compliance information, professionals can refer to the European Chemicals Agency (ECHA) official database:
https://echa.europa.eu/substance-information/-/substanceinfo/100.014.194

This authoritative link strengthens data transparency and helps industry experts verify REACH registration status, CLP classification, and exposure limits of n-Heptane (CAS 142-82-5) under European regulatory frameworks.

High-purity n-Heptane (≥99%) has established itself as a critical solvent in diverse industrial applications, ranging from pharmaceuticals and chemical synthesis to precision cleaning and laboratory research. Its exceptional purity, combined with ultra-low levels of contaminants, ensures optimal performance and safety across demanding processes.

With increasing global regulatory requirements, such as the European Union REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) regulation, high-purity chemical products now require compliance for entry into major markets, including Europe and Japan. REACH compliance not only guarantees legal market access but also reflects a company’s commitment to safety, environmental responsibility, and product quality.

Key Features and Advantages

Ultra-High Purity n-Heptane ≥99% ensures minimal interference in chemical reactions and formulations. Low Benzene (<1 ppm) and low aromatic content (<10 ppm) guarantee safety, regulatory compliance, and suitability for sensitive applications. Superior Chemical Performance Provides excellent solvency for non-polar compounds. Ideal for applications requiring consistent evaporation rates and minimal residue. Compatible with a variety of chemical systems, supporting both laboratory-scale and industrial-scale processes. Reliable and Consistent Supply Produced under stringent quality control to maintain batch-to-batch consistency. Packaged and delivered in secure containers to preserve purity during transport. Supports large-scale operations while providing small sample sizes for testing and evaluation. Global Compliance: REACH and Beyond REACH Overview: The EU REACH regulation, effective since June 1, 2007, governs the registration, evaluation, authorisation, and restriction of chemicals to protect human health and the environment. Registration: Companies must register chemical substances with the European Chemicals Agency (ECHA) to legally market products in the EU. Evaluation: ECHA evaluates submitted dossiers and chemical substances to ensure compliance and safety. Authorisation & Restriction: Certain substances require explicit authorisation for use, and hazardous chemicals may be restricted or banned. Applicability: REACH covers chemical substances across industries, including chemical manufacturing, electronics, automotive, construction, consumer products, healthcare, and more. Enhancement: Our high-purity n-Heptane complies with REACH standards, ensuring safe and legal entry into Europe and Japan, while demonstrating adherence to the highest international safety and environmental regulations. Versatile Applications Pharmaceuticals: Active ingredient extraction and purification. Electronics: Precision cleaning and solvent applications. Coatings and Adhesives: High-quality formulations requiring pure solvents. Laboratory Use: Analytical and research-grade solvent for controlled experiments.

Why Choose Our n-Heptane

Guaranteed Purity: Ensures your processes remain unaffected by impurities. Consistent Quality: Reliable batch-to-batch uniformity supports industrial-scale operations. Safe and Compliant: Low benzene and aromatic content reduce health and environmental risks; fully compliant with REACH regulations. Flexible Packaging: From small iron can samples to bulk ISO tanks, meeting all operational needs. Trusted Global Supply: Enables businesses to confidently operate in international markets without quality compromise.

Conclusion

High-purity n-Heptane ≥99% is a cornerstone for industries that demand precision, reliability, and safety. Coupled with REACH compliance, our products provide manufacturers and laboratories with:

Legal and safe access to European and Japanese markets Consistent performance and high-quality end products Compliance with international environmental and safety standards

By choosing high-purity n-Heptane, businesses ensure superior process performance, regulatory confidence, and long-term reliability, making it an indispensable solvent for global industrial applications.

Dear Partners and Industry Colleagues in Vietnam,

We are honored to announce our participation in the Vietnam Medipharm Expo 2026, hosted by the Ministry of Health of Vietnam in Ho Chi Minh City. At this important gathering, Junyuan Petroleum Group will present our high-purity n-Hexane and n-Heptane solutions, both fully certified under the European REACH regulation.

Unlocking Market Opportunities in Vietnam

Vietnam is experiencing rapid growth in healthcare and pharmaceuticals. By 2025, the country’s healthcare spending is projected to reach USD 23.3 billion, with USD 2.3 billion dedicated to medical equipment alone. Yet, the industry remains heavily reliant on imports, and much of the infrastructure requires urgent modernization.

This creates strong demand for high-quality raw materials and precision manufacturing inputs. From pharmaceutical extraction and synthesis to medical device cleaning and analytical quality control, the choice of solvents directly impacts safety, efficacy, and compliance.

Junyuan’s REACH-Certified Solutions

At Junyuan Petroleum Group, we recognize the critical role of solvents in pharmaceutical and medical applications. Our REACH-certified n-Hexane and n-Heptane are not just products – they are strategic enablers for your market access, compliance, and competitiveness.

1. Ultra-High Purity & Consistency

Exceptional low-impurity levels and reliable batch stability. Ensure precise, repeatable outcomes in GC, HPLC, and analytical testing. A trusted foundation for laboratory and production quality assurance.

2. Global Compliance Advantage

REACH certification guarantees the highest standards of safety and environmental responsibility. Provides a seamless export passport to the EU and other global markets. Demonstrates compliance with international regulations from the very start of your supply chain.

3. Key Application Scenarios

Pharmaceutical Manufacturing: Ideal as an efficient and safe solvent for extraction and purification of active pharmaceutical ingredients (APIs). Medical Device Cleaning: Effective for precision instruments, endoscopes, and surgical tools – leaving no residue and ensuring consistent performance. Analytical Testing: Widely used as a top-grade mobile phase or diluent in chromatography, supporting drug analysis and medical device residue testing.

Partnering for Vietnam’s Future

At Junyuan Petroleum Group, our mission is to become a trusted foundation for Vietnam’s healthcare and pharmaceutical advancement. By choosing our REACH-certified n-Hexane and n-Heptane, you are aligning with global standards of safety, compliance, and reliability, giving your products a decisive edge in international markets.

We warmly invite you to visit us at the Vietnam Medipharm Expo 2026:

📅 July 30 – August 1, 2026

📍 Saigon Exhibition & Convention Center (SECC), Ho Chi Minh City

Our technical experts will be on-site to provide comprehensive product insights and tailored application solutions. Together, let us explore new opportunities to fuel your business growth and support Vietnam’s industry transformation.

We look forward to meeting you in Ho Chi Minh City!

Sincerely,

Junyuan Petroleum Group

On August 28, the 17th Oil Trade Fair of the Yellow River Delta (Dongying) and Global Energy Festival 2025 officially opened. Guided by the China Petroleum Chamber of Commerce and hosted by the Dongying Petroleum Chamber of Commerce, the two-day event brought together leaders from more than 20 provincial and municipal petroleum chambers, the African Business Alliance, Cameroonian petroleum representatives, leading global petrochemical companies, and major domestic enterprises including Sinopec, CNPC, CNOOC, and Air China Petroleum. Participants also included producers of naphtha, MTBE, aromatics, and alkylates, as well as shipping, logistics, wholesale, storage, oil quality improvement companies, and key end customers.

Junyuan Petroleum Group, as Vice President Unit of the Dongying Petroleum Chamber of Commerce, actively participated in the fair to promote its products, strengthen customer relationships, and explore future industry opportunities. The event, themed “Global Energy Empowering New Industrial Energy Development,” featured market briefings, technology showcases, discussion forums, project collaborations, and trade negotiations—offering a platform for resource sharing, complementary advantages, and win-win partnerships among petrochemical enterprises.

At the exhibition, Junyuan Petroleum highlighted its full solvent portfolio, including n-Pentane, n-Hexane, Isopentane, Cyclopentane, and notably n-Heptane, which has recently obtained REACH certification. This achievement demonstrates the company’s commitment to international regulatory compliance, high-quality products, and providing clients with reliable, globally recognized solutions for chemical, pharmaceutical, and industrial applications.

Through active engagement at the fair, Junyuan’s team gained insight into the latest industry trends, deepened connections with clients, and laid a solid foundation for expanding market reach. Moving forward, the team will continue to integrate resources, enhance collaboration with partners, and drive business growth to a new level.