Tag European market

n-Heptane Overview

n-Heptane (CAS No. 142-82-5, EC No. 205-563-8) is a straight-chain hydrocarbon (C₇H₁₆) recognized throughout the European regulatory framework as a key industrial solvent. It is classified under the CLP Regulation Annex VI and officially registered in ECHA’s Registered Substances Database, confirming its full REACH compliance for import and use across the European Economic Area (EEA) at volumes exceeding 1,000 tonnes per year.

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Substance Names and Other Identifiers

Main substance name:

• n-Heptane

Other common names and synonyms:

• Heptane
• Heptan
• Heptanen
• Dipropylmethane
• Dipropyl methane
• Heptyl hydride
• Normal heptane
• Heptane (all isomers)
• Heptane [99.0% for HPLC Solvent]
• Heptane [and isomers]
• n-Heptano
• Gettysolve-C
• Skellysolve C
• Eptani
• Hydrocarbon solvents

Regulatory process names:

• Heptane
• Heptane; n-Heptane
• n-Heptane
• heptane/n-heptane

Translated names (examples):

• Heptan, n-Heptan (German)
• Heptan, N-heptan (Romanian)

Trade names:

• Heptane
• n-Heptane

Identifiers:

• CAS number: 142-82-5
• EC number: 205-563-8
• Index number: 601-008-00-2
• Other CAS numbers (legacy or related): 44607-13-8, 8031-33-2

IUPAC names:

• Dipropylmethane
• n-Heptane

Regulatory and Directive references:
n-Heptane is listed under multiple EU regulations and directives, including:

General Product Safety Regulation – Hazardous Substances

REACH Registration Dossier

EC Inventory

C&L Inventory

Pre-registration process

Aerosols Directive – Flammable Contents

Chemical Agents Directive (CAD) – Hazardous Agents

Ambient Air Quality Directive, Annex X – Ozone Precursor Substances

Occupational Exposure Limits (OELVs) – Indicative List

Construction Products Regulation – Hazardous Substances (Annex I & Art. 6)

EU Ecolabel Regulation – Hazardous Substance Restrictions

Medical Devices Directives and Regulations – Hazardous Substances

Pressure Equipment Directive – Group 1 Fluids

Waste Framework Directive – Annex III Hazardous Properties

Fertiliser Regulation, Annex I, E.3 – Chelating/Complexing Agents

Due to its extensive industrial and scientific use, n-Heptane is known under a wide range of regulatory, IUPAC, and trade names across different European legislations and databases.

Regulatory Process Names:
Dipropyl Methane, Eptani, Gettysolve-C, Heptan, Heptane, Heptanen, Heptyl Hydride, n-Heptane, Skellysolve C

Translated Names (EU languages):

• Heptan / n-Heptan (DE) – German
• Heptan / N-heptan (RO) – Romanian

IUPAC and Technical Names:
Dipropylmethane, n-Heptane, Heptane (all isomers), Heptane [99.0% for HPLC Solvent], Normal Heptane, Hydrocarbon Solvent

Trade Names:
Heptane, n-Heptane, Gettysolve-C, Skellysolve C

Identifiers:

• CAS Number: 142-82-5 (Main)
• EC Number: 205-563-8
• Index Number (CLP): 601-008-00-2
• Other CAS Numbers: 44607-13-8, 8031-33-2
• Molecular Formula: C₇H₁₆

These identifiers appear consistently across EINECS, C&L Inventory, REACH Pre-registration, and multiple EU regulatory annexes, ensuring full traceability and transparency in supply.

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Regulatory Framework and Compliance

n-Heptane is explicitly listed under numerous European chemical and environmental legislations, highlighting its regulated yet accepted status in industrial and laboratory operations:

• REACH Regulation – Registered substance (≥1000 tpa)
• CLP Regulation Annex VI – Harmonized classification & labeling
• Seveso III Directive Annex I – Industrial accident prevention
• Waste Framework Directive Annex III – Hazardous properties
• Occupational Exposure Limits (OELs) – Indicative EU OELVs
• Construction Products Regulation (Annex I & Art.6(5))
• EU Ecolabels & Environmental Policy Framework Directive
• Medical Devices Regulation / Directive (Hazardous Substances)
• General Product Safety Regulation & Workplace Safety Directive

This extensive inclusion across directives confirms that n-Heptane is both recognized and regulated for controlled industrial use, making it an ideal choice for European manufacturers seeking long-term compliant sourcing.

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Applications Across European Industries

n-Heptane’s versatility has established it as a critical raw material and process solvent in:

• Pharmaceutical manufacturing – extraction, crystallization, and purification
• Laboratories – high-purity analytical use (HPLC, GC)
• Coatings and adhesives – solvent and viscosity control
• Automotive and fuel industry – reference standard for octane rating
• Cleaning and degreasing agents – controlled volatility applications

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Safety and Environmental Management

Classified as a highly flammable liquid (H225), skin irritant (H315), and toxic to aquatic life (H410), n-Heptane must be handled with professional containment, proper labeling, and full compliance to the GHS/CLP system.
Manufacturers provide complete Safety Data Sheets (SDS) and Guidance on Safe Use, aligned with the Chemical Agents Directive (CAD) and Pressure Equipment Directive.

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Why Choose Our n-Heptane

Fully REACH-registered and CLP compliant
High-purity grades (up to 99%) for pharmaceutical and analytical use
Stable European supply in ISO tanks or drums
Complete documentation package (SDS, COA, technical data)
Proven compliance with EU industrial, medical, and environmental standards

Our n-Heptane product line delivers consistency, safety, and full regulatory transparency for European customers in pharmaceuticals, R&D, and specialty chemicals manufacturing.

For technical details, safety classifications, and compliance information, professionals can refer to the European Chemicals Agency (ECHA) official database:
https://echa.europa.eu/substance-information/-/substanceinfo/100.014.194

This authoritative link strengthens data transparency and helps industry experts verify REACH registration status, CLP classification, and exposure limits of n-Heptane (CAS 142-82-5) under European regulatory frameworks.

Abstract:
n-Heptane (CAS 142-82-5; EC 205-563-8) is a registered substance under the European Union’s REACH regulation, enabling its safe and compliant use across diverse industries. As a mono-constituent substance of petroleum origin, n-Heptane is registered for tonnage bands exceeding 1,000 tonnes per year, ensuring wide availability for European buyers. The REACH registration dossier highlights its extensive applications, including as a solvent in manufacturing, a fuel additive, a component in coatings and adhesives, and in laboratory processes. Businesses sourcing n-Heptane in the EU should request REACH certificates, Safety Data Sheets (SDS), and confirmation of tonnage coverage from suppliers to guarantee regulatory compliance. For downstream users, verifying that specific applications are covered in the supplier’s dossier is crucial, while importers must ensure valid registration via their EU-based entity or Only Representative. With its robust regulatory framework and versatile uses, n-Heptane is positioned as a reliable, compliant, and high-value solvent and process material in the European market.

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n-Heptane and REACH Registration in the EU

n-Heptane has been successfully registered under the EU’s REACH regulation (Registration, Evaluation, Authorisation and Restriction of Chemicals). The registration process ensures that the substance complies with stringent European standards for safety, environmental impact, and responsible use.

• Identifiers:
  • CAS Number: 142-82-5
  • EC Number: 205-563-8
  • Typical Registration Number Format: 01-2119457603-38-xxxx
• Substance Type:
  n-Heptane is registered as a mono-constituent substance, most commonly of petroleum origin.
• Tonnage Band:
  Registrations cover >1,000 tonnes per year, reflecting its broad industrial demand.

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Industrial Applications of n-Heptane

The versatility of n-Heptane makes it an essential material across multiple European industries. Key applications include:

• Solvent in manufacturing processes – widely used in adhesives, coatings, and extraction processes.
• Fuel and fuel additives – supporting clean combustion and blending.
• Cleaning agents – valued for its efficiency in dissolving oils and greases.
• Laboratory applications – as a reference solvent and calibration standard.
• Formulations – incorporated into paints, coatings, and industrial adhesives.

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Compliance Documentation for Buyers

To ensure smooth operations and full compliance, buyers in the EU should request the following documents from suppliers:

1. REACH Certificate – official proof that the product is registered under REACH.
2. Safety Data Sheet (SDS) – including the REACH registration number and hazard/safety guidance.
3. Confirmation of Tonnage Coverage – assurance that the supplier’s registration covers the required quantity and intended use.

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Obligations for Buyers in the EU

• Downstream Users:
  Businesses that use n-Heptane in production must confirm that their applications are included in the supplier’s registration dossier. The SDS will provide this detail.
• Importers:
  If n-Heptane is imported from outside the EU, the responsibility for REACH registration lies with the importer. Alternatively, the non-EU manufacturer can appoint an “Only Representative” to manage registration on their behalf. In both cases, importers should obtain the valid REACH registration number.

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Conclusion

With full REACH registration, n-Heptane is a reliable and compliant material for European industries. Its wide-ranging applications, regulatory approval, and high-volume availability position it as a critical solvent and process chemical. By sourcing from trusted suppliers and ensuring the proper documentation, buyers can secure both regulatory compliance and uninterrupted supply.

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Keywords:
n-Heptane, REACH compliance, European market, solvent, coatings, adhesives, fuel additive, laboratory applications, CAS 142-82-5, EC 205-563-8