— Supporting High-Standard Compliance in the Pharmaceutical Industry

We are pleased to announce that our n-Heptane (CAS No.: 142-82-5) has successfully obtained EU REACH 1000MT+ registration, marking a significant step forward in regulatory compliance, safety, and market access. This achievement highlights our commitment to regulatory excellence and sustainable supply in the global chemical market.

Applications of n-Heptane in the Pharmaceutical Industry

In the pharmaceutical sector, n-Heptane is an essential organic solvent widely used across analysis, purification, and formulation development. Its non-polar nature and high purity make it an ideal choice in various drug manufacturing processes:

• Solvent Functions: Used for extraction, crystallization, and separation processes, particularly effective in purifying active pharmaceutical ingredients (APIs) or intermediates.
• Chromatographic Analysis: Serves as a standard solvent for gas chromatography (GC) or high-performance liquid chromatography (HPLC), facilitating accurate analysis of drug components and impurities.
• Formulation Development: Acts as an excipient or process solvent in certain formulations, assisting coating, granulation, and drying processes.
• Cleaning Agent: Suitable for cleaning equipment or glassware, especially in water-sensitive production processes.
• Reference Material: Employed in pharmacopeial testing as a standard for instrument calibration or method validation.

Significance of REACH Registration

REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) is one of the strictest chemical regulatory frameworks worldwide. Achieving 1000MT+ registration allows us to legally supply over 1,000 tons of n-Heptane annually to the EU market, backed by comprehensive physical-chemical, toxicological, and environmental assessments.

This milestone reflects our dedication to quality and regulatory compliance while strengthening our competitive edge across the pharmaceutical, coatings, rubber, ink, and specialty chemical industries.

Safety and Compliance

n-Heptane is volatile and possesses neurotoxic potential. It should be handled in well-ventilated areas with appropriate protective measures. We uphold the principles of safety, environmental responsibility, and regulatory compliance to provide customers with high-standard chemical solutions and technical support.

For technical data sheets (TDS), MSDS, or regulatory support documents related to n-Heptane, please feel free to contact us.

#Heptane #nHeptane #REACH #PharmaceuticalSolvent #GreenChemistry #ChemicalCompliance

In pharmaceutical manufacturing, purity is more than a specification — it’s a promise. Every solvent plays a critical role in ensuring product safety, consistency, and regulatory compliance. That’s why we’re proud to introduce our premium-grade n-Heptane, produced by the only REACH-registered manufacturer in China.

Why Choose Our n-Heptane

• REACH-Certified for Europe We are the sole Chinese producer of n-Heptane officially registered under the EU REACH regulation. This guarantees full compliance for import and use across European markets, including Italy.
• Pharmaceutical-Grade Purity With purity levels exceeding 99%, our n-Heptane meets the stringent requirements of pharmaceutical applications — from active ingredient extraction to crystallization and cleaning processes.
• Reliable Supply and Documentation We offer consistent production capacity, flexible packaging options, and complete technical documentation including COA and MSDS, ensuring smooth procurement and regulatory alignment.
• Dedicated Support for European Clients Our experienced export team provides clear communication, fast response times, and full assistance with logistics coordination and compliance paperwork.

Bridging Chinese Manufacturing with European Standards

Our REACH certification is more than a regulatory milestone — it’s a symbol of our long-term commitment to quality, safety, and partnership. We understand the expectations of European pharmaceutical companies and deliver accordingly.

Let’s Build a Smarter, Safer Supply Chain Together

Whether you’re optimizing your sourcing strategy or seeking a more compliant and cost-effective alternative, our n-Heptane is ready to meet your needs.

n-Heptane (CAS No.: 142-82-5) is a widely used non-polar organic solvent in pharmaceuticals, coatings, and specialty chemical industries. While its high purity and versatile applications make it an essential industrial chemical, it is important to understand its flash point, a critical property for safe handling and storage.

What is Flash Point?

The flash point of a liquid is the lowest temperature at which it can vaporize to form a combustible mixture with air. At or above this temperature, a spark or flame can ignite the vapor, potentially causing fire or explosion. Understanding flash points is fundamental for classifying chemicals, selecting storage conditions, and implementing safety measures.

Flash Point of n-Heptane

n-Heptane is highly flammable, with a flash point of approximately −4°C (24.8°F). This extremely low value indicates that n-Heptane can easily form flammable vapors at room temperature, emphasizing the need for caution during handling.

Safety Implications

Because of its low flash point, n-Heptane requires careful handling to minimize fire hazards:

• Storage: Keep in tightly sealed containers, away from heat, sparks, and open flames.
• Ventilation: Use in well-ventilated areas to prevent vapor accumulation.
• Personal Protection: Wear flame-resistant clothing and appropriate gloves and goggles.
• Grounding and Bonding: When transferring n-Heptane between containers, ensure proper grounding to avoid static sparks.

Industrial Relevance

Understanding n-Heptane’s flash point is not only important for laboratory and industrial safety but also for regulatory compliance. It helps chemical manufacturers, distributors, and end-users comply with fire safety regulations, REACH guidelines, and occupational health standards.

Conclusion

The flash point of n-Heptane is a key physical property that underscores its high flammability. Proper knowledge, storage, and handling practices ensure that this versatile solvent can be safely used in pharmaceutical, coating, and specialty chemical applications.

#nHeptane #Heptane #ChemicalSafety #FlashPoint #PharmaceuticalSolvent #FlammableLiquids #ChemicalCompliance

At Junyuan Petroleum Group’s flagship facility, our newly commissioned alkane adsorption separation unit is now delivering 99.9% ultra-high-purity n-Hexane—a pharmaceutical-grade intermediate essential for precision synthesis. Its exceptional chemical stability minimizes side reactions, enabling tighter control over drug yields and manufacturing consistency.

Since first commercializing n-Hexane with >99.6% purity in December 2006, Junyuan has continuously advanced its production capabilities. As of August 2025, we’ve become China’s first petroleum-based producer of ultra-high-purity n-Hexane, replacing imported alternatives and setting new standards for domestic chemical manufacturing.

This breakthrough reflects Junyuan’s enduring commitment to innovation in energy and fine chemicals—where purity, reliability, and performance are mission-critical.

Follow Junyuan Petroleum Group for more milestones in precision engineering and industrial excellence.

In the competitive landscape of industrial chemicals, quality, reliability, and purity define success. Our premium high-purity pentanes – including n-Pentane, Isopentane, and Cyclopentane – are engineered to meet the strictest technical standards required by manufacturers in electronics, pharmaceuticals, adhesives, and refrigeration industries.

Our products are designed to directly compete with industry leaders such as SK and LG, offering equivalent or superior performance and purity. They are distinguished by:

Isopentane purity above 99%, ensuring stable and predictable performance in refrigeration systems and high-precision applications. Ultra-low impurity levels, with cyclic pentanes below 100 ppm, light fractions under 0.5%, and total sulfur under 1 ppm. Negligible aromatic content, with benzene below 10 ppm, and non-volatile residues less than 1 mg/100 ml, ideal for sensitive chemical processes.

These specifications reflect our commitment to chemical purity, process safety, and regulatory compliance. Having successfully supplied demanding Asian markets, our pentanes have proven their consistent quality, excellent performance, and strong reputation. This regional success confirms our ability to support global industrial partners who require high-grade pentanes for critical applications.

Whether used as solvents, foam-blowing agents, or high-purity chemical intermediates, our pentanes provide industrial users with uncompromising quality, reliable supply, and peace of mind. Partner with us to access world-class pentanes designed to match or outperform leading competitors in the market.

High-purity n-Heptane (≥99%) has established itself as a critical solvent in diverse industrial applications, ranging from pharmaceuticals and chemical synthesis to precision cleaning and laboratory research. Its exceptional purity, combined with ultra-low levels of contaminants, ensures optimal performance and safety across demanding processes.

With increasing global regulatory requirements, such as the European Union REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) regulation, high-purity chemical products now require compliance for entry into major markets, including Europe and Japan. REACH compliance not only guarantees legal market access but also reflects a company’s commitment to safety, environmental responsibility, and product quality.

Key Features and Advantages

Ultra-High Purity n-Heptane ≥99% ensures minimal interference in chemical reactions and formulations. Low Benzene (<1 ppm) and low aromatic content (<10 ppm) guarantee safety, regulatory compliance, and suitability for sensitive applications. Superior Chemical Performance Provides excellent solvency for non-polar compounds. Ideal for applications requiring consistent evaporation rates and minimal residue. Compatible with a variety of chemical systems, supporting both laboratory-scale and industrial-scale processes. Reliable and Consistent Supply Produced under stringent quality control to maintain batch-to-batch consistency. Packaged and delivered in secure containers to preserve purity during transport. Supports large-scale operations while providing small sample sizes for testing and evaluation. Global Compliance: REACH and Beyond REACH Overview: The EU REACH regulation, effective since June 1, 2007, governs the registration, evaluation, authorisation, and restriction of chemicals to protect human health and the environment. Registration: Companies must register chemical substances with the European Chemicals Agency (ECHA) to legally market products in the EU. Evaluation: ECHA evaluates submitted dossiers and chemical substances to ensure compliance and safety. Authorisation & Restriction: Certain substances require explicit authorisation for use, and hazardous chemicals may be restricted or banned. Applicability: REACH covers chemical substances across industries, including chemical manufacturing, electronics, automotive, construction, consumer products, healthcare, and more. Enhancement: Our high-purity n-Heptane complies with REACH standards, ensuring safe and legal entry into Europe and Japan, while demonstrating adherence to the highest international safety and environmental regulations. Versatile Applications Pharmaceuticals: Active ingredient extraction and purification. Electronics: Precision cleaning and solvent applications. Coatings and Adhesives: High-quality formulations requiring pure solvents. Laboratory Use: Analytical and research-grade solvent for controlled experiments.

Why Choose Our n-Heptane

Guaranteed Purity: Ensures your processes remain unaffected by impurities. Consistent Quality: Reliable batch-to-batch uniformity supports industrial-scale operations. Safe and Compliant: Low benzene and aromatic content reduce health and environmental risks; fully compliant with REACH regulations. Flexible Packaging: From small iron can samples to bulk ISO tanks, meeting all operational needs. Trusted Global Supply: Enables businesses to confidently operate in international markets without quality compromise.

Conclusion

High-purity n-Heptane ≥99% is a cornerstone for industries that demand precision, reliability, and safety. Coupled with REACH compliance, our products provide manufacturers and laboratories with:

Legal and safe access to European and Japanese markets Consistent performance and high-quality end products Compliance with international environmental and safety standards

By choosing high-purity n-Heptane, businesses ensure superior process performance, regulatory confidence, and long-term reliability, making it an indispensable solvent for global industrial applications.

Polyurethane Rigid Foam (PUR) is a high-performance, closed-cell insulation material widely used in cold storage, cold-chain logistics, industrial refrigeration, and other low-temperature insulation applications. Its excellent thermal insulation, structural stability, and adaptability make it the material of choice for modern insulation projects.

Its core advantages include:

1. Outstanding Thermal Insulation

Low Thermal Conductivity: PUR exhibits thermal conductivity as low as 0.018–0.024 W/(m·K), making it one of the most effective insulation materials currently available. This reduces energy loss and lowers operational costs. High Closed-Cell Content (≥90%): The closed-cell structure blocks air convection, enhances moisture resistance, and prevents performance degradation due to water vapor infiltration.

Enhancement: The use of high-purity Cyclopentane, Isopentane, or n-Pentane as blowing agents ensures that the foam maintains its low thermal conductivity and closed-cell integrity over time, directly contributing to superior insulation efficiency.

2. Structural Strength and Durability

Compressive Strength and Deformation Resistance: With densities typically ranging from 35–60 kg/m³ and compressive strengths of 150–300 kPa, PUR can support internal racks, equipment, and transport loads. Dimensional Stability: Maintains its volume across extreme temperatures (-50°C to +100°C) with minimal shrinkage or cracking, ensuring long-term reliability.

Enhancement: The controlled purity of pentane-based blowing agents (<2 ppm sulfur, <50 ppm moisture) prevents defects during production and guarantees that the foam retains its strength and dimensional stability throughout its lifecycle.

3. Easy Installation and Adaptability

On-Site Spraying / Pouring: PUR can be applied seamlessly onto walls, roofs, or cavities, eliminating thermal bridges and providing a continuous insulation layer. Compatibility with Multiple Substrates: Bonds firmly to concrete, metal sheets, and composite panels, making it ideal for complex cold storage structures.

Enhancement: Using optimized pentane blends ensures uniform foam expansion and adhesion, improving application efficiency and minimizing material waste.

4. Environmental Friendliness and Safety

Low Global Warming Potential (GWP): Modern PUR systems employ environmentally friendly blowing agents such as Cyclopentane, Isopentane, or water-based formulations, reducing environmental impact. Fire Safety: With proper flame retardants, PUR can achieve B1-class flame resistance (GB 8624-2012), meeting stringent cold storage fire standards.

Enhancement: Our high-purity pentane products are fully compliant with international environmental regulations, providing a sustainable and safe option for manufacturers aiming to meet both GWP and fire safety requirements.

5. Economic Advantages

Although initial costs may be higher than traditional materials like EPS or rock wool, PUR’s long lifespan (20+ years) and energy-saving properties significantly reduce operating costs.

Enhancement: By selecting our reliable pentane blowing agents, manufacturers can achieve consistent foam quality and maximize energy efficiency, enhancing ROI over the lifetime of the insulation system.

Application Considerations

Controlled Installation Environment: Surfaces must be dry and clean; recommended temperature is 15–35°C with humidity below 85%. Insulation Thickness Design: Determined by the target cold storage temperature (e.g., -18°C for refrigeration or -60°C for ultra-low temperature). Typical PUR layers range from 50–150 mm. Safety Protection: Workers must wear protective gear to avoid exposure to uncured chemicals.

Enhancement: Using high-purity pentane ensures predictable foam behavior even under varying environmental conditions, reducing installation risk and ensuring design specifications are met.

Why Pentane-Based Blowing Agents Are Critical

The superior performance of PUR depends directly on the quality of the blowing agent. Our Cyclopentane, Isopentane, and n-Pentane products offer:

Purity Control: Low sulfur (<2 ppm) and low moisture (<50 ppm) for defect-free foam. Processing Stability: Uniform cell structure for optimal insulation and mechanical strength. Versatility: Suitable for a wide range of applications including cold storage, refrigerated trucks, and PIR/PUR panels. Environmental Compliance: Non-ozone-depleting, low GWP, aligned with global regulations.

Conclusion

Polyurethane Rigid Foam remains the top choice for modern cold storage insulation, offering unparalleled thermal performance, durability, and adaptability. High-purity pentane-based blowing agents are essential to fully realize these benefits, ensuring:

Maximum thermal insulation efficiency Consistent structural integrity Reliable production and long-term performance Compliance with environmental and fire safety standards

By choosing our products, manufacturers can deliver high-quality, energy-efficient, and environmentally responsible insulation solutions, ensuring optimal performance for decades.

n-Pentane 95%: Cost-Effective Blowing Agent for Insulation and Industrial Applications

Introduction

As industries worldwide move toward energy efficiency and sustainable construction, demand for versatile and affordable raw materials continues to grow. One such material is n-Pentane 95%, a high-performance hydrocarbon solvent widely recognized for its role in insulation foam manufacturing and industrial formulations.

Why Choose n-Pentane 95%?

Optimized Purity for Industrial Use

• Guaranteed 95% purity ensures consistent quality.
• Ideal for large-scale industrial applications where ultra-high purity is unnecessary.
• Balances performance and cost efficiency, making it a preferred choice for manufacturers.

Preferred Blowing Agent in Insulation Panels

• Extensively used in PU (polyurethane) and PIR (polyisocyanurate) sandwich panels.
• Common applications: roofing boards, cold storage insulation panels, and energy-saving construction materials.
• Compatible with modern production lines, helping manufacturers meet regional energy-efficiency standards.

Cost Efficiency

• More economical compared to higher-purity solvents.
• Attractive for bulk procurement and regular industrial use.
• Delivers reliable results without compromising application performance.

Versatile Industrial Applications

• Applied in adhesives, coatings, and cleaning formulations.
• Fast evaporation rate enhances efficiency in manufacturing processes.
• Reliable solvent properties make it suitable across multiple industrial sectors.

Packaging and Logistics

• Supplied in ISO tanks, steel drums, or customized bulk packaging.
• Logistics partners ensure compliance with international hazardous goods regulations.
• Safe and timely delivery for global clients.

Market Outlook

• Rapid construction growth in the Middle East, Asia, and emerging markets drives demand.
• Rising focus on energy-saving insulation materials strengthens n-Pentane’s role in sustainable infrastructure.
• n-Pentane 95% remains a cornerstone raw material for manufacturers delivering cost-effective, high-quality solutions.

Industry Transformation Creates Certainty in Uncertain Times

The European chemical industry is undergoing a historic transformation. With global giants such as Dow, INEOS, Shell, and others closing or downsizing key production facilities, the region’s supply landscape is shifting dramatically. By the end of 2027, Europe is expected to lose approximately 4.6 million tons/year of ethylene capacity, directly reshaping the downstream solvent market. Among these, n-Heptane is facing a structural supply shortage, even as demand remains resilient.

Market Restructuring and the Emerging Supply Gap

Recent plant closures highlight this dramatic shift:

Dow will shut down its ethylene cracker in Böhlen, Germany (510,000 t/y capacity) by 2027 INEOS permanently closed its phenol and acetone facilities in Gladbeck, Germany Westlake Chemical ceased operations at its Pernis, Netherlands site (150,000 t/y BPA) Celanese shut down its VAM plant in Frankfurt, Germany

These moves have pushed Europe’s chemical capacity utilization rate down to 74%, the lowest in decades. The resulting contraction in local supply capabilities has amplified the shortage of critical solvents, including n-Heptane, across pharmaceutical, coatings, adhesive, and rubber industries.

Junyuan Petroleum Group’s Advantage: Compliance + Reliability

Amid this uncertainty, Junyuan Petroleum Group provides a stable and fully compliant n-Heptane supply to European customers, backed by REACH registration and stringent quality standards.

Key Advantages:

Full REACH Compliance – Seamless market access for European clients. Stable Production Base – China-based facilities unaffected by Europe’s energy crisis. Cost Competitiveness – Significant advantage vs. European producers (EU natural gas prices are 3.3x higher than the U.S.). High Purity Guarantee – n-Heptane purity reaching 99.9%, meeting the demands of high-end applications.

Core Applications:

Pharmaceuticals – extraction solvent, crystallization medium Coatings & Inks – thinner and cleaning agent Adhesives – reaction medium and diluent Rubber Processing – solvent and extraction agent

Partnership Opportunities: Building Resilient Supply Chains

We offer European partners flexible collaboration models to ensure long-term stability and performance:

Sample Supply & Technical Dossiers – including full REACH documentation Flexible Delivery Solutions – from trial orders to long-term supply contracts Technical Support – tailored application guidance and customized solutions

Conclusion: Turning Market Disruption into Growth

The restructuring of Europe’s chemical industry is creating new opportunities in the n-Heptane supply chain. With REACH-certified, high-purity, and cost-effective products, Junyuan Petroleum Group is ready to support European customers in building reliable, sustainable, and future-ready supply networks.

Contact us today to request product details, technical documents, or samples, and secure your competitive advantage in this evolving market.

Cyclopentane, a seemingly simple cyclic hydrocarbon, plays a crucial role in numerous industrial sectors, including refrigeration, materials, and chemical manufacturing. Its unique structure and properties have a profound impact on modern industrial processes and everyday life.

1. Structure and Properties: A Stable Cyclic Molecule

Cyclopentane, with the molecular formula C₅H₁₀, is a saturated cycloalkane featuring a five-membered ring. Carbon atoms are connected by single bonds, forming a stable cyclic structure that imparts distinct physical and chemical properties.

Physically, cyclopentane is a colorless liquid with a gasoline-like odor, a melting point of −94.4°C, a boiling point of 49.3°C, a relative density of 0.746 (water=1), and a relative vapor density of 2.42 (air=1). It is insoluble in water but miscible with many organic solvents such as alcohols, ethers, benzene, carbon tetrachloride, and acetone. Its relatively low boiling point gives it volatility at ambient temperatures.

Chemically, cyclopentane exhibits typical alkane stability and low reactivity. While it generally resists addition reactions, it can undergo halogenation, cracking, and other reactions under high temperature, light, or catalytic conditions. Compared to unsaturated hydrocarbons like alkenes or alkynes, its reactivity is comparatively low.

2. Production Process: Petroleum-Derived Refinement

Cyclopentane is primarily derived from petroleum through processes such as distillation and catalytic cracking. Fractions containing cyclopentane are further refined and purified to achieve high-purity products. Industrially, cyclopentane with purity above 98% is typically obtained through fractional distillation of petroleum ether fractions with boiling points in the 30–60°C range. Alternative methods, including cyclopentanone reduction or catalytic hydrogenation of cyclopentadiene, exist but are less common due to higher complexity and cost.

Technological improvements in catalysts and process optimization have significantly increased production efficiency and product quality while reducing manufacturing costs.

3. Production Capacity and Output

In 2024, global cyclopentane production capacity surpassed 3 million tons per year, with an output of approximately 2.2 million tons, maintaining a capacity utilization rate of 70–75%. Asia (especially China), North America, and Europe constitute the core production regions. China alone accounts for 1.2 million tons of capacity and 850,000 tons of output, representing 40% and 38.6% of global totals, respectively.

Global production grew at an average annual rate of 6.5% over the past five years. In China, due to advantages in appliance cooling and polyurethane foam clusters, annual growth reached 8.2%, surpassing the global average. Despite a temporary slowdown to 5.1% in 2023–2024 due to domestic capacity closures and weaker overseas demand, global output is projected to grow at 7% CAGR from 2025–2030, with China remaining a key growth hub.

4. Market Participants and Competitiveness

Global and Chinese cyclopentane markets are dominated by several types of players:

International specialty chemical leaders: High technological barriers, producing ultra-high-purity cyclopentane (>99.9%) for semiconductor cleaning and precision instruments. Integrated refining companies: Cost-efficient, leveraging full petroleum refining processes to supply industrial-grade cyclopentane with high purity. Regional market specialists: Focus on specific areas (e.g., Asia, North America) and provide tailored products compliant with local environmental regulations. Appliance industry-focused suppliers: Major domestic suppliers specializing in refrigeration foam applications, offering customized formulations and fast delivery. Export-oriented producers: High-purity products compliant with international standards (e.g., REACH), targeting global markets. Emerging environmentally friendly producers: Develop low-GWP and sustainable production processes, aligning with global carbon reduction trends.

5. Applications: Multifaceted Industrial Roles

Refrigeration and Insulation: Cyclopentane is an eco-friendly blowing agent for rigid polyurethane foam, replacing ozone-depleting CFCs/HCFCs. Widely used in refrigerators, freezers, cold storage, and insulated pipelines. Chemical and Materials Industry: Acts as a solvent in organic synthesis, coatings, inks, and petroleum refining. Serves as a precursor for polymers such as polycyclopentene, used in plastics, rubber, automotive components, building materials, and electronics. Other Uses: Standard for chromatographic analysis, fuel additive, and environmentally friendly industrial cleaners.

6. Safety and Environmental Considerations

Cyclopentane is highly flammable, forming explosive mixtures with air. Strict fire and explosion prevention, ventilation, and trained personnel are essential. As a VOC, its emissions may contribute to air pollution and aquatic toxicity. Effective exhaust treatment and emission control are required to minimize environmental impact.

Conclusion

Cyclopentane’s unique cyclic structure and versatile properties make it indispensable across multiple industrial sectors. With advancing technology and rising environmental standards, its applications will expand further. At the same time, stringent safety and environmental management are critical to ensure sustainable use.